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Table 2 Changes in the Child–Pugh scores, Child–Pugh stages

From: TIPS improves outcomes in patients with HCC and symptomatic portal hypertension: a multi-institution experience

Variable Before TIPS One month after TIPS P
Response to TIPSb
 CR   92(74.8%)  
 PR   23(18.7%)  
 NR   8(6.5%)  
Child–Pugh stage    0.006*
 A 32(26.0%) 56(45.5%)  
 B 79(64.2%) 58(47.2%)  
 C 12(9.8%) 9(7.3%)  
Change of Child–Pugh stageb
 Down   41(33.3%)  
 Unchanged   70(56.9%)  
 Elevated   12(9.8%)  
 Child–Pugh scores 8(6-9) 7(6-8) <0.001**
Change of Child–Pugh scoresb
 Down   73(59.3%)  
 Unchanged   28(22.8%)  
 Elevated   22(17.9%)  
HEa    1.000*
 I/II 4(3.3%) 12(9.8%)  
 III/IV 0 1(0.8%)  
Grading of ascites
 0/1 56(45.5%) 107(87.0%) <0.001*
 2/3 67(54.5%) 16(13.0%)  
Bilirubin(IQRa, umol/L) 29.5(19.2-41.0) 37.4(25.6-48.1) <0.001**
 <34 75(61.0%) 51(41.4%)  
 ≥34 48(39.0%) 72(58.6%)  
Albumin (g/L) 33.2(30.2-36.8) 34.7(33.1-36.8) 0.134**
 <35 72(58.5%) 65(52.8%)  
 ≥35 51(41.5%) 58(47.2%)  
PT(s)a 14.2(13.1-15.6) 15.5(14.1-17.1) <0.001**
 Prolonged < 6 117(95.1%) 71(57.7%)  
 Prolonged ≥6 6(4.9%) 52(42.3%)  
  1. aHE Hepatic encephalopathy, PT prothrombin time; bOne month after TIPS, the Child-Pugh stage and Child-Pugh score were reassessed. The responses to TIPS: complete response (CR), no further variceal bleeding and having no clinically detectable ascites with or without diuretic or salt-restricted diet; partial response (PR), having a small amount of ascites not requiring special paracentesis; and nonresponse (NR), having a large amount of ascites needing special intervention or variceal bleeding recurrence. *Chi-square test; **Paired t-test