Dynamic contrast-enhanced MRI radiomics nomogram for predicting axillary lymph node metastasis in breast cancer

Cancer Imaging

Table 1 Clinical characters and radiomics score of the training and validation cohort

characteristic	training cohort			Validation cohort
characteristic	Positive for ALN metastasis(n = 106)	Negative for ALN metastasis (n = 190)	P value	Positive for ALN metastasis(n = 54)	Negative for ALN metastasis(n = 82)	P value
Age (mean ± SD)	53.94 ± 9.66	53.84 ± 10.07	0.727	52.35 ± 11.14	53.20 ± 9.17	0.373
Tumor size (mm)	20.37 ± 4.87	19.95 ± 4.67	0.723	20.44 ± 5.88	19.14 ± 4.72	0.500
Histological grade			<0.001*			<0.001*
I	13	56		3	20
II	64	108		32	53
III	29	26		19	9
Multifocality			<0.001*			0.001*
Yes	53	54		29	19
No	53	136		25	63
MRI report LN status			<0.001*			0.006*
Yes	74	81		34	32
No	32	109		20	50
Estrogen receptor			0.030*			0.734
Positive	84	128		39	57
Negative	22	62		15	25
Progesterone receptor			0.930			0.928
Positive	72	130		34	51
Negative	34	60		20	31
HER2 status			0.340			0.897
Positive	30	64		12	19
Negative	76	126		42	63
Ki-67 status			0.881			0.210
Positive	75	136		41	54
Negative	31	54		13	28
Radiomics score	−0.008(−0.55 to 0.36)	−1.642(−2.40 to −0.72)	<0.001*	0.064(−0.47 to 0.52)	−1.613(−2.67 to −0.63)	<0.001*

Note: Data are number of patients; Data in the last line in parentheses are interquartile ranges
LN lymph node, HER2 human epidermal growth factor receptor 2, SD standard deviation
^*highlights the p values that are smaller than 0.05

ISSN: 1470-7330