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Table 4 Univariate and multivariate Cox regression model with other established risk factors for median OS

From: Quantitative washout in patients with hepatocellular carcinoma undergoing TACE: an imaging biomarker for predicting prognosis?

Analysis Univariate Multivariate
Covariate HR 95% CI P-value HR 95% CI P-value
Age ≥ 70 years 0.9 0.6–1.6 0.800    
BCLC Stage C or D 2.1 1.1–4.0 0.034 1.4 0.6–3.2 0.384
AFP >  200 ng/ml 1.5 0.8–2.6 0.190    
Albumin level ≥ 35 g/l 2.3 1.2–4.3 0.010 1.8 0.9–3.6 0.121
Bilirubin level ≥ 1.2 mg/dl 2.7 1.5–4.7 < 0.001 2.5 1.4–4.5 0.003
AST level >  31 U/L 2.5 0.6–10 0.210    
ALT level ≥ 35 U/L 1.0 0.6–1.7 0.980    
INR > 1.2 1.0 0.6–1.8 0.910    
Platelet count <  100/mm3 1.3 0.8–2.3 0.270    
Multifocality Yes 1.3 0.6–2.6 0.490    
Tumor size >  5.0 cm 1.8 1.0–3.1 0.041 1.7 0.9–3.2 0.125
DPAR >  120 1.4 0.8–2.3 0.260    
  1. AFP, alpha fetoprotein. AST, aspartate aminotransferase. ALT, alanine aminotransferase. BCLC, Barcelona Clinical Liver Cancer. DPAR, delayed percentage attenuation ratio.