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Table 4 Univariate and multivariate Cox regression model with other established risk factors for median OS

From: Quantitative washout in patients with hepatocellular carcinoma undergoing TACE: an imaging biomarker for predicting prognosis?

Analysis

Univariate

Multivariate

Covariate

HR

95% CI

P-value

HR

95% CI

P-value

Age

≥ 70 years

0.9

0.6–1.6

0.800

   

BCLC

Stage C or D

2.1

1.1–4.0

0.034

1.4

0.6–3.2

0.384

AFP

>  200 ng/ml

1.5

0.8–2.6

0.190

   

Albumin level

≥ 35 g/l

2.3

1.2–4.3

0.010

1.8

0.9–3.6

0.121

Bilirubin level

≥ 1.2 mg/dl

2.7

1.5–4.7

< 0.001

2.5

1.4–4.5

0.003

AST level

>  31 U/L

2.5

0.6–10

0.210

   

ALT level

≥ 35 U/L

1.0

0.6–1.7

0.980

   

INR

> 1.2

1.0

0.6–1.8

0.910

   

Platelet count

<  100/mm3

1.3

0.8–2.3

0.270

   

Multifocality

Yes

1.3

0.6–2.6

0.490

   

Tumor size

>  5.0 cm

1.8

1.0–3.1

0.041

1.7

0.9–3.2

0.125

DPAR

>  120

1.4

0.8–2.3

0.260

   
  1. AFP, alpha fetoprotein. AST, aspartate aminotransferase. ALT, alanine aminotransferase. BCLC, Barcelona Clinical Liver Cancer. DPAR, delayed percentage attenuation ratio.
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