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Table 2 Results of univariate analysis in the training cohort for predicting LN metastasis

From: Radiomics nomogram for the preoperative prediction of lymph node metastasis in pancreatic ductal adenocarcinoma

Variables Statistics Odds Ratio (95% CI) P value
Rad-score (median, interquartile range) 0 (− 0.45–0.46) 3.25 (1.99, 5.33) < 0.0001
Rad-score
 Q1 41 (22.8) 1.0 (reference)  
 Q2 41 (22.8) 1.89 (0.76, 4.71) 0.1712
 Q3 48 (26.8) 4.03 (1.65, 9.82) 0.0022
 Q4 50 (27.8) 8.57 (3.32, 22.13) < 0.0001
 Age (y, mean ± SD) 60.5 + 8.8 0.97 (0.94, 1.01) 0.1167
 BMI (kg/m2, mean ± SD) 22.6 + 2.7 1.00 (0.90, 1.12) 0.9987
Sex
 Male 107 (59.4) 1.0 (reference)  
 Female 73 (40.6) 0.90 (0.49, 1.63) 0.7257
CA 19–9
  < 1000 μg/L 122 (67.8) 1.0 (reference)  
 ≥1000 μg/L 58 (32.2) 1.24 (0.66, 2.34) 0.5011
Location
 Head 107 (59.4) 1.0 (reference)  
 Neck, body and tail 73 (40.6) 0.68 (0.37, 1.24) 0.2062
T grade
 T1 22 (12.2) 1.0 (reference)  
 T2 38 (21.1) 2.68 (0.91, 7.94) 0.0746
 T3–4 120 (66.7) 2.29 (0.89, 5.86) 0.0845
Differentiation grade
 Well to moderately 150 (83.3) 1.0 (reference)  
 Poorly to undifferentiated 30 (16.7) 0.67 (0.30, 1.47) 0.3168
 Size (mm, median, interquartile range) 25.01 (19.0–31.6) 1.01 (0.98, 1.04) 0.5712
Vascular invasion
 No 110 (61.1) 1.0 (reference)  
 Yes 70 (38.9) 1.05 (0.57, 1.92) 0.8779
Organ invasion
 No 158 (87.8) 1.0 (reference)  
 Yes 22 (12.2) 1.21 (0.49, 2.99) 0.6809
CT-reported LN status
 Negative 118 (65.6) 1.0 (reference)  
 Positive 62 (34.4) 2.25 (1.18, 4.28) 0.0136
  1. Data are presented as n (%)
  2. Rad-score radiomics score, LN lymph node, CA19–9 carbohydrate antigen 19–9, CI confidence interval
  3. Patients were categorized into quartiles by radiomics score (Q1 < -0.45, Q2 [−0.45 to 0], Q3 [0 to 0.46], and Q4 ≥ 0.46)