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Table 2 Comparison of clinicopathological characteristics in widths of wall rigidity-positive lesions and -negative lesions under profile view of barium enema

From: Role of barium enema examination for the diagnosis of submucosal invasion depth in T1 colorectal cancers

  Horizontal rigidity-positive Horizontal rigidity-negative P-value Vertical rigidity -positive Vertical rigidity -negative P-value
  (88 lesions) (57 lesions) (108 lesions) (37 lesions)
Tumor size, n (%) < 20 mm 55 (62.5) 36 (63.2) 1.0 68 (63) 23 (62.2) 1.0
  ≥20 mm 33 (37.5) 21 (36.8) 40 (37) 14 (37.8)
Location, n (%) Right side of the colon 22 (25) 16 (28.1) 0.70 30 (27.5) 8 (21.6) 0.52
  Left side of the colon 66 (75) 41 (71.9) 78 (72.2) 29 (78.4)
Morphology, n (%) Protruding type 55 (62.5) 20 (35.1) 0.002 60 (55.6) 15 (40.5) 0.13
  Superficial type 33 (37.5) 37 (64.9) 48 (44.4) 22 (59.5)
JNET classification, n (%) 1/2A/2B 39 (44.3) 43 (75.4) 0.0003 54 (50) 28 (75.7) 0.007
  3 49 (55.7) 14 (24.6) 54 (50) 9 (24.3)
Pit pattern classification, n (%) I/II/IIIL/IIIs/IV/VI low- irregularity 11 (12.5) 18 (31.6) 0.01 17 (15.7) 12 (32.4) 0.03
  VI high-irregularity/VN 77 (87.5) 39 (68.4) 91 (84.3) 25 (67.6)
Histologic type, n (%) Well/mod/pap 86 (97.7) 57 (100) 0.52 106 (98.2) 37 (100) 1.0
  Por/sig/muc 2 (2.3) 0 (0) 2 (1.8) 0 (0)
Depth of submucosal invasion, n (%) < 1.8 mm 12 (13.6) 41 (71.9) 0.0001 24 (22.2) 29 (78.4) 0.0001
  ≥1.8 mm 76 (86.4) 16 (28.1) 84 (77.8) 8 (21.6)
Lympho-vascular invasion, n (%) Positive 38 (43.2) 10 (17.5) 0.002 41 (38) 7 (18.9) 0.03
  Negative 50 (56.8) 47 (82.5) 67 (62) 30 (81.1)
Tumor budding, n (%) Grade 1 78 (88.6) 53 (93) 0.57 96 (88.9) 35 (94.6) 0.52
  Grade 2/3 10 (11.4) 4 (7) 12 (11.1) 2 (5.4)
Lymph node metastasis, n (%) Positive 7 (8.6) 4 (12.1) 0.73 9 (9.6) 2 (10) 1.0
(Only lesions removed surgically) Negative 74 (91.4) 29 (87.9) 85 (90.4) 18 (90)
  1. Horizontal rigidity-positive is defined as horizontal rigidity ≥4.5 mm. Vertical rigidity-positive is defined as vertical rigidity ≥0.7 mm
  2. Continuous values are indicated as mean ± SD (standard deviation). JNET: Japan narrow-band imaging expert team
  3. well well differentiated adenocarcinoma, mod moderately differentiated adenocarcinoma, pap papillary adenocarcinoma, poor poorly differentiated adenocarcinoma, sig signet-ring cell carcinoma, muc mucinous adenocarcinoma