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Table 3 Median values and main statistics of the DCE-MRI and IVIM-DWI parameters (Wilcoxon test; paired t-test and Bland-Altman analysis). Values with the # symbol were statistically significant at P<0.05.

From: DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases

Main cohort (n=25) Ktrans (nz) EF KEF D D* f fD*
Median value [Visit 1] 0.109 91.2 0.095 0.00083 0.0166 0.0947 0.0014
Median value [Visit 2] 0.078 50.8 0.045 0.00097 0.0095 0.1091 0.0011
P value (Wilcoxon signed-rank test) 0.002# <0.001# <0.001# <0.001# 0.14 0.43 0.09
IVIM Repeatability cohort (n=5) Ktrans(nz) EF KEF D D* f fD*
Mean value [Repeat 1] x x x 0.0012 0.0348 0.0885 0.0027
Mean value [Repeat 2] x x x 0.0012 0.0404 0.1065 0.0045
P value (paired t-test)     0.57 0.61 0.44 0.41
Bland-Altman tests  
standard deviation (SD)     0.00003 0.022 0.047 0.004
mean bias     -0.00001 0.006 0.018 0.002
coefficient of variation (CV) %; SD/mean     2.9 60 48 117
  1. nz=nonzeros