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Table 3 Median values and main statistics of the DCE-MRI and IVIM-DWI parameters (Wilcoxon test; paired t-test and Bland-Altman analysis). Values with the # symbol were statistically significant at P<0.05.

From: DCE-MRI is more sensitive than IVIM-DWI for assessing anti-angiogenic treatment-induced changes in colorectal liver metastases

Main cohort (n=25)

Ktrans (nz)

EF

KEF

D

D*

f

fD*

Median value [Visit 1]

0.109

91.2

0.095

0.00083

0.0166

0.0947

0.0014

Median value [Visit 2]

0.078

50.8

0.045

0.00097

0.0095

0.1091

0.0011

P value (Wilcoxon signed-rank test)

0.002#

<0.001#

<0.001#

<0.001#

0.14

0.43

0.09

IVIM Repeatability cohort (n=5)

Ktrans(nz)

EF

KEF

D

D*

f

fD*

Mean value [Repeat 1]

x

x

x

0.0012

0.0348

0.0885

0.0027

Mean value [Repeat 2]

x

x

x

0.0012

0.0404

0.1065

0.0045

P value (paired t-test)

   

0.57

0.61

0.44

0.41

Bland-Altman tests

 

standard deviation (SD)

   

0.00003

0.022

0.047

0.004

mean bias

   

-0.00001

0.006

0.018

0.002

coefficient of variation (CV) %; SD/mean

   

2.9

60

48

117

  1. nz=nonzeros