Fig. 2
VOI-based data processing (example of one slice out of the 8 evaluated) for a 48 year old female patient with a lesion in segments 7/8 of the liver. VOI was drawn on the highest-b-value image (a), then transferred to the DCE-MRI subtraction image (b). The subtraction image was calculated as the difference between the dynamic image with peak enhancement within the liver parenchyma (dynamic 9/40) and the first pre-contrast image (dynamic 1/40). The VOIs were used in conjunction with each of the computed maps to derive the median values of parameters of interest: D (c) and Ktrans (d) are shown here. Note that Ktrans map is shown overlaid on the last dynamic image of the DCE-MRI acquisition (dynamic 40/40)