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Table 4 Diagnostic efficacy of ADC-pre, MD-pre, MK-pre, Dslow-pre and PRE

From: Comparison of the pre-treatment functional MRI metrics’ efficacy in predicting Locoregionally advanced nasopharyngeal carcinoma response to induction chemotherapy

  AUC 95%CI Youden Cutoff sensitivity specificity +LR -LR +PV -PV
ADC-pre
(×10−6 mm2/s)
0.885 (0.772,0.955) 0.650 1210 75.00% 90.00% 7.50 0.28 93.1 66.7
MD-pre
(×10−6 mm2/s)
0.855 (0.735,0.935) 0.556 1010 80.6% 75.0% 3.22 0.26 85.3 68.2
MK-pre
(×10−6)
0.692 (0.555,0.809) 0.394 832 94.4% 45.0% 1.72 0.12 75.6 81.8
Dslow-pre
(×10−6 mm2/s)
0.742 (0.608,0.850) 0.450 835 75.00% 70.00% 2.50 0.36 81.8 60.9
PRE 0.912 (0.806,0.971) 0.672 0.799 72.22% 95.00 14.44 0.29 96.3 65.5
  1. Abbreviation: AUC: area under the curve; 95% CI: 95% confidence interval; +LR: positive likelihood ratio; −LR: negative likelihood ratio; +PV: positive predictive value; −PV: negative predictive value