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Table 3 The fMRI parameters with statistical differences between RG and NRG

From: Comparison of the pre-treatment functional MRI metrics’ efficacy in predicting Locoregionally advanced nasopharyngeal carcinoma response to induction chemotherapy

  RG(n = 36) NRG(n = 20) t/U p
D-post (cm) 1.18 (0.68) 1.94 (0.98) 113.500 0.000Δ
ΔD (cm) −1.27 (0.59) −0.4 (0.54) 52.000 0.000Δ
ΔD% −49.24%(24.14) −18.62 (11.71) 0.000 0.000Δ
V –post (cm3) 4.80 (8.97) 11.68 (10.08) 177.000 0.002Δ
ΔV (cm3) −10.48 (9.11) −4.92 (4.17) 152.000 0.000Δ
ΔV % −64.98 ± 17.77 −30.35 ± 14.94 7.377 0.000
ADC-pre (×10−6mm2/s) 1119.58 ± 144.06 1386.25 ± 198.23 5.790 0.000
ADC-post (×10−6mm2/s) 1410.00 (258) 1557.00 (320) 106.000 0.002Δ
ΔADC% 33.81 (30) 18.14 (30) 206.500 0.430Δ
MD-pre (×10−6mm2/s) 902.00 (150) 1121.00 (331) 104.500 0.000Δ
ΔMD (×10− 6mm2/s) 504.46 ± 106.51 318.90 ± 242.72 −3.023 0.004
ΔMD% 58.56 ± 20.49 28.61 ± 21.77 −4.666 0.000
MK-pre (×10−6) 1052.25 ± 122.02 935.10 ± 185.34 −2.538 0.017
ΔMK (×10−6) 492.00 (217) 305.00 (144) 129.000 0.009Δ
ΔMK% 60.92 (20) 28.17 (14) 131.000 0.010Δ
Dslow-pre (×10−6mm2/s) 724.50 ± 235.92 933.85 ± 219.95 3.258 0.002
  1. Abbreviations: D: diameters of tumor (cm); V: volume of tumor (cm3); ADC: apparent diffusion coefficient (×10−6 mm2/s), MD: mean diffusion (× 10− 6 mm2/s), MK: mean kurtosis (× 10− 6), Dslow: true diffusion coefficient (× 10− 6 mm2/s). Statistical analysis was performed using the independent-samples t test were marked with “Δ” (data were reported as mean values ± standard error), while using Mann-Whitney U test were marked with” ”(data were presented as median (interquartile range))