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Table 3 The fMRI parameters with statistical differences between RG and NRG

From: Comparison of the pre-treatment functional MRI metrics’ efficacy in predicting Locoregionally advanced nasopharyngeal carcinoma response to induction chemotherapy

 

RG(n = 36)

NRG(n = 20)

t/U

p

D-post (cm)

1.18 (0.68)

1.94 (0.98)

113.500

0.000Δ

ΔD (cm)

−1.27 (0.59)

−0.4 (0.54)

52.000

0.000Δ

ΔD%

−49.24%(24.14)

−18.62 (11.71)

0.000

0.000Δ

V –post (cm3)

4.80 (8.97)

11.68 (10.08)

177.000

0.002Δ

ΔV (cm3)

−10.48 (9.11)

−4.92 (4.17)

152.000

0.000Δ

ΔV %

−64.98 ± 17.77

−30.35 ± 14.94

7.377

0.000

ADC-pre (×10−6mm2/s)

1119.58 ± 144.06

1386.25 ± 198.23

5.790

0.000

ADC-post (×10−6mm2/s)

1410.00 (258)

1557.00 (320)

106.000

0.002Δ

ΔADC%

33.81 (30)

18.14 (30)

206.500

0.430Δ

MD-pre (×10−6mm2/s)

902.00 (150)

1121.00 (331)

104.500

0.000Δ

ΔMD (×10− 6mm2/s)

504.46 ± 106.51

318.90 ± 242.72

−3.023

0.004

ΔMD%

58.56 ± 20.49

28.61 ± 21.77

−4.666

0.000

MK-pre (×10−6)

1052.25 ± 122.02

935.10 ± 185.34

−2.538

0.017

ΔMK (×10−6)

492.00 (217)

305.00 (144)

129.000

0.009Δ

ΔMK%

60.92 (20)

28.17 (14)

131.000

0.010Δ

Dslow-pre (×10−6mm2/s)

724.50 ± 235.92

933.85 ± 219.95

3.258

0.002

  1. Abbreviations: D: diameters of tumor (cm); V: volume of tumor (cm3); ADC: apparent diffusion coefficient (×10−6 mm2/s), MD: mean diffusion (× 10− 6 mm2/s), MK: mean kurtosis (× 10− 6), Dslow: true diffusion coefficient (× 10− 6 mm2/s). Statistical analysis was performed using the independent-samples t test were marked with “Δ” (data were reported as mean values ± standard error), while using Mann-Whitney U test were marked with” ”(data were presented as median (interquartile range))