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Table 2 The comparison of fMRI parameters before and after IC

From: Comparison of the pre-treatment functional MRI metrics’ efficacy in predicting Locoregionally advanced nasopharyngeal carcinoma response to induction chemotherapy

  Pre-IC Post-IC t/Z p
ADC (× 10−6mm2/s) 1238.43 ± 211.932 1549.84 ± 242.527 −11.441 .000
MD (×10−6mm2/s) 1012.50 ± 223.836 1432.61 ± 252.577 −12.603 .000
MK (×10−6) 1020.00 (183) 779.00 (226) −5.485 .000Δ
Dslow (×10−6mm2/s) 778.00 (370) 937.00 (548) −3.227 .001Δ
Dfast (× 10−4mm2/s) 410.59 ± 181.513 363.16 ± 170.045 2.729 .009
PF (×10−4) 198.50 (103) 243.00 (109) −2.165 .030Δ
Ktrans(×10−3/min) 920.43 ± 549.753 790.48 ± 445.798 1.543 .130
Ve (×10−3) 686.18 ± 242.582 838.14 ± 235.443 −3.205 .003
Kep (×10−3/min) 1239.50 (945) 805.00 (679) −3.019 .003Δ
  1. Abbreviations: IC: induction chemotherapy; ADC: apparent diffusion coefficient(×10−6 mm2/s), MD: mean diffusion (× 10− 6 mm2/s), MK: mean kurtosis (× 10− 6), Dslow: true diffusion coefficient(× 10− 6 mm2/s), Dfast: pseudo diffusion coefficient (× 10− 4 mm2/s), PF: perfusion fraction (× 10− 4), Ktrans: volume transfer constant (× 10− 3/min), Ve: extracellular extravascular space (× 10− 3), Kep: rate constant(× 10− 3/min). Statistically significant differences determined by Paired t test are marked with “” (data were reported as mean values ± standard error), while Wilcoxon rank-sum test are marked with” Δ” (data were presented as median (interquartile range))