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Table 2 The comparison of fMRI parameters before and after IC

From: Comparison of the pre-treatment functional MRI metrics’ efficacy in predicting Locoregionally advanced nasopharyngeal carcinoma response to induction chemotherapy

 

Pre-IC

Post-IC

t/Z

p

ADC (× 10−6 mm2/s)

1238.43 ± 211.932

1549.84 ± 242.527

−11.441

.000♦

MD (×10−6 mm2/s)

1012.50 ± 223.836

1432.61 ± 252.577

−12.603

.000♦

MK (×10−6)

1020.00 (183)

779.00 (226)

−5.485

.000Δ

Dslow (×10−6 mm2/s)

778.00 (370)

937.00 (548)

−3.227

.001Δ

Dfast (× 10−4 mm2/s)

410.59 ± 181.513

363.16 ± 170.045

2.729

.009♦

PF (×10−4)

198.50 (103)

243.00 (109)

−2.165

.030Δ

Ktrans(×10−3/min)

920.43 ± 549.753

790.48 ± 445.798

1.543

.130♦

Ve (×10−3)

686.18 ± 242.582

838.14 ± 235.443

−3.205

.003♦

Kep (×10−3/min)

1239.50 (945)

805.00 (679)

−3.019

.003Δ

  1. Abbreviations: IC: induction chemotherapy; ADC: apparent diffusion coefficient(×10−6 mm2/s), MD: mean diffusion (× 10− 6 mm2/s), MK: mean kurtosis (× 10− 6), Dslow: true diffusion coefficient(× 10− 6 mm2/s), Dfast: pseudo diffusion coefficient (× 10− 4 mm2/s), PF: perfusion fraction (× 10− 4), Ktrans: volume transfer constant (× 10− 3/min), Ve: extracellular extravascular space (× 10− 3), Kep: rate constant(× 10− 3/min). Statistically significant differences determined by Paired t test are marked with “♦” (data were reported as mean values ± standard error), while Wilcoxon rank-sum test are marked with” Δ” (data were presented as median (interquartile range))
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Cancer Imaging

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