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Table 2 Histogram parameters of apparent diffusion coefficient (ADC) maps and T2weighted (T2W) images in patients with prostate cancer (PCa) and benign prostatic hyperplasia (BPH)

From: Differentiating prostate cancer from benign prostatic hyperplasia using whole-lesion histogram and texture analysis of diffusion- and T2-weighted imaging

  Parameters PCa (n = 90) BPH (n = 112) p-value
ADC 5th percentile 557.661 ± 131.688 795.973 ± 116.08 < 0.0001
Mean 806.754 ± 131.268 988.752 ± 106.763 < 0.0001
Median 788.539 ± 140.309 979.942 ± 111.27 < 0.0001
Std 176.311 ± 48.874 129.004 ± 45.47 < 0.0001
Diff-Variance 0.195 ± 0.032 0.178 ± 0.04 < 0.0001
Diff-Entropy 0.757 ± 0.099 0.707 ± 0.086 < 0.0001
Contrast 0.628 ± 0.231 0.488 ± 0.21 < 0.0001
Entropy 1.748 ± 0.289 1.605 ± 0.234 < 0.0001
95th percentile 1123.756 ± 169.511 1217.362 ± 142.675 < 0.0001
Skewness 0.472 ± 0.597 0.297 ± 0.575 0.026
Kurtosis 0.419 ± 1.212 0.315 ± 1.311 0.386
T2W Kurtosis 2.272 ± 2.179 1.375 ± 1.598 0.001
Skewness 0.851 ± 0.558 0.631 ± 0.413 0.001
5th percentile 171.594 ± 43.653 193.165 ± 45.757 0.001
Median 259.822 ± 54.330 278.165 ± 54.817 0.014
Std 68.67 ± 20.296 61.937 ± 18.164 0.012
Mean 267.630 ± 56.500 283.756 ± 55.486 0.039
Entropy 2.355 ± 0.291 2.362 ± 0.279 0.797
Diff-Variance 0.589 ± 0.178 0.570 ± 0.162 0.578
95th percentile 391.011 ± 88.876 393.134 ± 78.278 0.759
Diff-Entropy 1.467 ± 0.158 1.459 ± 0.157 0.808
Contrast 1.847 ± 0.689 1.851 ± 0.665 0.954
  1. Std standard deviation, Diff-Variance difference in variance, Diff-Entropy difference in entropy