Differentiating prostate cancer from benign prostatic hyperplasia using whole-lesion histogram and texture analysis of diffusion- and T2-weighted imaging

Table 2 Histogram parameters of apparent diffusion coefficient (ADC) maps and T2weighted (T2W) images in patients with prostate cancer (PCa) and benign prostatic hyperplasia (BPH)

	Parameters	PCa (n = 90)	BPH (n = 112)	p-value
ADC	5^th percentile	557.661 ± 131.688	795.973 ± 116.08	< 0.0001
	Mean	806.754 ± 131.268	988.752 ± 106.763	< 0.0001
	Median	788.539 ± 140.309	979.942 ± 111.27	< 0.0001
	Std	176.311 ± 48.874	129.004 ± 45.47	< 0.0001
	Diff-Variance	0.195 ± 0.032	0.178 ± 0.04	< 0.0001
	Diff-Entropy	0.757 ± 0.099	0.707 ± 0.086	< 0.0001
	Contrast	0.628 ± 0.231	0.488 ± 0.21	< 0.0001
	Entropy	1.748 ± 0.289	1.605 ± 0.234	< 0.0001
	95^th percentile	1123.756 ± 169.511	1217.362 ± 142.675	< 0.0001
	Skewness	0.472 ± 0.597	0.297 ± 0.575	0.026
	Kurtosis	0.419 ± 1.212	0.315 ± 1.311	0.386
T2W	Kurtosis	2.272 ± 2.179	1.375 ± 1.598	0.001
	Skewness	0.851 ± 0.558	0.631 ± 0.413	0.001
	5^th percentile	171.594 ± 43.653	193.165 ± 45.757	0.001
	Median	259.822 ± 54.330	278.165 ± 54.817	0.014
	Std	68.67 ± 20.296	61.937 ± 18.164	0.012
	Mean	267.630 ± 56.500	283.756 ± 55.486	0.039
	Entropy	2.355 ± 0.291	2.362 ± 0.279	0.797
	Diff-Variance	0.589 ± 0.178	0.570 ± 0.162	0.578
	95^th percentile	391.011 ± 88.876	393.134 ± 78.278	0.759
	Diff-Entropy	1.467 ± 0.158	1.459 ± 0.157	0.808
	Contrast	1.847 ± 0.689	1.851 ± 0.665	0.954

Std standard deviation, Diff-Variance difference in variance, Diff-Entropy difference in entropy

ISSN: 1470-7330