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Table 5 Hazard ratios of multiple clinical variables on uni- and multivariate survival analysis

From: Emergency room imaging in pediatric patients with cancer: analysis of the spectrum and frequency of imaging modalities and findings in a tertiary cancer center and their relationship with survival

Variable

Stratification

Univariate HR (95% CI)

p-value

Multivariate HR (95% CI)

p-value

ER imaging

Positive

2.84 (1.78–4.53)

<0.01

2.35 (1.44–3.83)

<0.01

Negative

1

reference

1

reference

Admission

Admitted

2.12 (1.34–3.30)

<0.01

1.86 (1.16–2.97)

<0.01

Discharged

1

reference

1

reference

Cancer type

CNS tumors

1.32 (0.72–2.43)

0.38

1.45 (0.78–2.70)

0.24

Hematologic malignancies

0.28 (0.14–0.56)

<0.01

0.25 (0.13–0.50)

<0.01

Neuroblastoma

0.72 (0.41–1.28)

0.26

0.62 (0.35–1.11)

0.11

Retinoblastoma

0.82 (0.32–2.11)

0.69

0.90 (0.35–2.33)

0.83

Others

0.77 (0.36–1.67)

0.51

0.64 (0.29–1.44)

0.28

Bone & soft tissue tumors

1

reference*

1

reference*

Gender

Male

1.10 (0.73–1.66)

0.66

  

Female

1

reference

  

Age (years)

11-18

0.95 (0.62–1.43)

0.79

  

0-10

1

reference

  

No. ER visits

≥3

2.96 (1.59–5.52)

<0.01

3.08 (1.62-5.83)

<0.01

2

1.97 (1.16–3.34)

 

1.98 (1.15–3.41)

0.01

1

1

reference

1

reference

  1. CI confidence interval, CNS central nervous system, ER emergency room, HR hazard ratio
  2. *Log-rank p-value <0.01 for analysis across all cancer types