CT-based multi-phase Radiomic models for differentiating clear cell renal cell carcinoma

Cancer Imaging

Table 2 Enhancement parameters of the lesion and its formulas

Enhancement parameters	Formulas	References
Lesion Attenuation Value	–
Absolute Deenhancement	T₃-T₂; T₄-T₃	[21]
Absolute Enhancement	T_2/3/4-T₁	[21]
Percentage Enhancement Ratio of Absolute Enhancement	(T_2/3/4-T₁)/T₁
Percentage Enhancement Ratio of renal cortex	C_1/2/3/4/ T_1/2/3/4	[22]
Percentage Enhancement Ratio of aorta	T_2/3/4/ A_2/3/4	[2]
Relative Attenuation of renal cortex	(T_1/2/3/4–C_1/2/3/4) / C_1/2/3/4	[21]
Relative Attenuation of aorta	(A_2/3/4–T_2/3/4) / A_2/3/4
Enhancement Change of renal cortex	C_1/2/3/4- T_1/2/3/4	[22]
Enhancement Change of aorta	A_2/3/4-T_2/3/4
Relative Enhancement Value of the Tumor (rTEV_2/3/4)	(T_2/3/4-T₁)/ (C_2/3/4-C₁)	[2]
Corrected CT values relative to aorta	(Sa/ A_2/3/4) *T_2/3/4
Corrected CT values relative to renal cortex	(Ac/ C_1/2/3/4) *T_1/2/3/4

Note: T1, T2, T3 and T4 represent the CT values of the tumors in unenhanced phase, corticomedullary phase, nephrographic phase, excretory phase respectively.C1, C2, C3 and C4 represent the CT values of normal renal cortex adjacent to the tumor in unenhanced phase, corticomedullary phase, nephrographic phase, excretory phase respectively. A2, A3 and A4 represent the CT values of the aorta in corticomedullary phase, nephrographic phase, excretory phase respectively. Sa represents the mean CT values of the corresponding layers of aorta in corticomedullary phase, nephrographic phase, and excretory phase respectively. Ac represents the mean CT value of the normal renal cortex adjacent to the tumor in unenhanced phase, corticomedullary phase, nephrographic phase, and excretory phase respectively

ISSN: 1470-7330