Fig. 2
From: Integrin αvβ6-targeted MR molecular imaging of breast cancer in a xenograft mouse model
In vitro targeting by laser scanning confocal microscopy (LSCM). a The 4 T1 and HEK293 cells were incubated with targeted cFK-9-AbFluor 647 or cFK-9-AbFluor 647 with excess cFK-9 peptides. A lower red fluorescence signal was detected in the 4 T1 membrane incubated with cFK-9-AbFluor 647 with excess cFK-9 peptides compared to cFK-9-AbFluor 647 only. In addition, the red fluorescence of 4 T1 cells incubated with cFK-9-AbFluor 647 is higher than HEK293 cells; b Quantitative analysis of 4 T1 and HEK293 cells by Image J bundled with 64-bit Java 1.8.0_112. *, p < 0.05; ***, p < 0.001