Table 1 Characteristics of patients in the training and testing cohorts
From: High resolution MRI-based radiomic nomogram in predicting perineural invasion in rectal cancer
Characteristics | Training cohort (n = 99) | Testing cohort (n = 41) | ||||
|---|---|---|---|---|---|---|
With PNI (n = 23) | Without PNI (n = 76) | P value | With PNI (n = 9) | Without PNI (n = 32) | P value | |
Age, mean ± SD, years | 63 ± 14 | 66 ± 9 | 0.400 | 66 ± 10 | 63 ± 9 | 0.421 |
Gender (%) | 0.891 | 0.092 | ||||
Male | 14 (60.9%) | 45 (59.2%) | 8 (88.9%) | 22 (68.8%) | ||
Female | 9 (39.1%) | 31 (40.8%) | 1 (11.1%) | 10 (31.2%) | ||
CEA, median (P25, P75), ng/mL | 3.00 (1.16,4.80) | 3.29 (1.87,7.12) | 0.249 | 5.10 (3.46,18.87) | 2.89 (1.76,8.61) | 0.127 |
CA199, median (P25, P75), ng/mL | 9.65 (5.30,15.83) | 12.42 (7.55,18.76) | 0.335 | 10.77 (6.71,20.65) | 14.26 (8.42,21.51) | 0.496 |
Histologic grade | 0.078 | 0.025 | ||||
Well differentiated | 1 (4.3%) | 15 (19.7%) | 0 (0) | 5 (15.6%) | ||
Moderately differentiated | 18 (78.3%) | 53 (69.7%) | 6 (66.7%) | 25 (78.1%) | ||
Poorly differentiated | 4 (17.4%) | 8 (10.5%) | 3 (33.3%) | 2 (6.3%) | ||
Primary site | 0.763 | 0.464 | ||||
Low | 8 (34.8%) | 28 (36.8%) | 1 (11.1%) | 8 (25.0%) | ||
Mid | 9 (39.1%) | 31 (40.8%) | 3 (33.3%) | 10 (31.3%) | ||
High | 6 (26.1%) | 17 (22.4%) | 5 (55.6%) | 14 (43.7%) | ||
Longest diameter, mean ± SD, cm | 5.71 ± 2.20 | 4.71 ± 1.97 | 0.041 | 5.22 ± 1.27 | 4.64 ± 1.90 | 0.161 |
mT-stage | < 0.00 | 0.089 | ||||
T1/T2 | 6 (26.1%) | 55 (72.4%) | 1 | 4 (44.4%) | 24 (75.0%) | |
T3 | 17 (65.4%) | 21 (27.6%) | 5 (55.6%) | 8 (25.0%) | ||
mLN-status | 0.187 | 0.507 | ||||
N0 | 10 (43.5%) | 45 (59.2%) | 7 (77.8%) | 21 (65.6%) | ||
N1-N2 | 13 (56.5%) | 31 (40.8%) | 2 (22.2%) | 11 (34.4%) | ||
CRM | 0.149 | 0.023 | ||||
Positive | 9 (39.1%) | 18 (23.7%) | 6 (66.7%) | 8 (25.0%) | ||
Negative | 14 (60.9%) | 58 (76.3%) | 3 (33.3%) | 24 (75.0%) | ||
EMVI | 0.008 | 0.637 | ||||
Positive | 11 (47.8%) | 15 (19.7%) | 3 (33.3%) | 8 (25.0%) | ||
Negative | 12 (52.2%) | 61 (80.3%) | 6 (66.7%) | 24 (75.0%) | ||