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Table 2 MRI sequences and tissue signal intensities [3, 8]

From: The value of bone marrow, liver, and spleen imaging in diagnosis, prognostication, and follow-up monitoring of myeloproliferative neoplasms: a systematic review

  T1-weighted spin-echo
(representing the sum of in-phase signals of fat and water)
STIR
(enhances the difference in longitudinal relaxation of fat and water)
Chemical shift imaging
(out-of-phase images visualizing the absolute difference between water and fat signals)
Fat High Low High
Water Low High High
Cellular marrow
(≈ 40% fat, 40% water, 20% protein)
Intermediate
(higher than muscle)
Intermediate
(higher than muscle)
Low
Fatty marrow
(≈ 80% fat, 15% water, 5% protein)
High Low High
Fibrosis Low Low Low
  1. MRI magnetic resonance imaging, STIR short tau inversion recovery
  2. In general, marrow characteristics are mainly based on its fat and water content, since bone lacks mobile protons [76]. Description of brightness is relative, as compared to the signal intensity of adjacent muscle or intervertebral disc
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