Table 2 The univariate analysis for recurrence in MTC patients
From: Ultrasound features of medullary thyroid cancer as predictors of biological behavior
| Variable | N | Recurrence | P | |
|---|---|---|---|---|
| No | Yes | |||
| Age (years) | 49.5 ± 12.1 | 53.4 ± 9.3 | 0.266a | |
| Preoperative Ct/tumor size (pg/mL/mm) | 32.15 | 51.68 | 0.002b | |
| Gender | 0.768 | |||
| Female | 38 | 31 (54.4) | 7 (50.0) | |
| Male | 33 | 26 (45.6) | 7 (50.0) | |
| Tumor size (cm) | 1.48 ± 0.96 | 1.81 ± 1.11 | 0.271 | |
| ≤ 1 | 30 | 26 (45.6) | 4 (28.6) | 0.247 |
| >1 | 41 | 31 (54.4) | 10 (71.4) | |
| Multifocality | 0.917 | |||
| Yes | 22 | 17 (29.8) | 5 (35.7) | |
| No | 49 | 40 (70.2) | 9 (64.3) | |
| Extrathyroid extension | 0.047 | |||
| Yes | 39 | 28 (49.1) | 11 (78.6) | |
| No | 32 | 29 (50.9) | 3 (21.4) | |
| Central node metastasisc | 0.000 | |||
| Yes | 30 | 18 (32.7) | 12 (85.7) | |
| No | 39 | 37 (67.3) | 2 (14.3) | |
| Lateral node metastasisd | 1.000 | |||
| Yes | 26 | 18 (78.3) | 8 (72.7) | |
| No | 8 | 5 (21.7) | 3 (27.3) | |
| T stage | 0.166 | |||
| T1 + T2 | 32 | 28 (49.1) | 4 (28.6) | |
| T3 + T4 | 39 | 29 (50.9) | 10 (71.4) | |
| N stage | 0.003 | |||
| N0 | 33 | 32 (56.1) | 1 (7.1) | |
| N1a | 12 | 7 (12.3) | 5 (35.7) | |
| N1b | 26 | 18 (31.6) | 8 (57.1) | |
| Preoperative Ct level (pg/mL) | 0.009 | |||
| ≤ 100 | 16 | 16 (28.1) | 0 (0.0) | |
| 100–1000 | 31 | 25 (43.9) | 6 (42.9) | |
| > 1000 | 24 | 16 (28.1) | 8 (57.1) | |
| Biochemical curee | 0.000 | |||
| Yes | 39 | 37 (78.7) | 2 (15.4) | |
| No | 21 | 10 (21.3) | 11 (84.6) | |
| Classification of TI-RADS | 0.013 | |||
| l-MTC | 22 | 22 (38.6) | 0 (0.0) | |
| m-MTC | 49 | 35 (61.4) | 14 (100.0) | |