Table 2 The univariate analysis for recurrence in MTC patients
From: Ultrasound features of medullary thyroid cancer as predictors of biological behavior
Variable | N | Recurrence | P | |
|---|---|---|---|---|
No | Yes | |||
Age (years) | 49.5 ± 12.1 | 53.4 ± 9.3 | 0.266a | |
Preoperative Ct/tumor size (pg/mL/mm) | 32.15 | 51.68 | 0.002b | |
Gender | 0.768 | |||
Female | 38 | 31 (54.4) | 7 (50.0) | |
Male | 33 | 26 (45.6) | 7 (50.0) | |
Tumor size (cm) | 1.48 ± 0.96 | 1.81 ± 1.11 | 0.271 | |
≤ 1 | 30 | 26 (45.6) | 4 (28.6) | 0.247 |
>1 | 41 | 31 (54.4) | 10 (71.4) | |
Multifocality | 0.917 | |||
Yes | 22 | 17 (29.8) | 5 (35.7) | |
No | 49 | 40 (70.2) | 9 (64.3) | |
Extrathyroid extension | 0.047 | |||
Yes | 39 | 28 (49.1) | 11 (78.6) | |
No | 32 | 29 (50.9) | 3 (21.4) | |
Central node metastasisc | 0.000 | |||
Yes | 30 | 18 (32.7) | 12 (85.7) | |
No | 39 | 37 (67.3) | 2 (14.3) | |
Lateral node metastasisd | 1.000 | |||
Yes | 26 | 18 (78.3) | 8 (72.7) | |
No | 8 | 5 (21.7) | 3 (27.3) | |
T stage | 0.166 | |||
T1 + T2 | 32 | 28 (49.1) | 4 (28.6) | |
T3 + T4 | 39 | 29 (50.9) | 10 (71.4) | |
N stage | 0.003 | |||
N0 | 33 | 32 (56.1) | 1 (7.1) | |
N1a | 12 | 7 (12.3) | 5 (35.7) | |
N1b | 26 | 18 (31.6) | 8 (57.1) | |
Preoperative Ct level (pg/mL) | 0.009 | |||
≤ 100 | 16 | 16 (28.1) | 0 (0.0) | |
100–1000 | 31 | 25 (43.9) | 6 (42.9) | |
> 1000 | 24 | 16 (28.1) | 8 (57.1) | |
Biochemical curee | 0.000 | |||
Yes | 39 | 37 (78.7) | 2 (15.4) | |
No | 21 | 10 (21.3) | 11 (84.6) | |
Classification of TI-RADS | 0.013 | |||
l-MTC | 22 | 22 (38.6) | 0 (0.0) | |
m-MTC | 49 | 35 (61.4) | 14 (100.0) | |