Table 2 Imaging Features of Fumarate Hydratase-Deficient Renal Cell Carcinoma
From: Imaging features of fumarate hydratase-deficient renal cell carcinomas: a retrospective study
| Imaging Features | n (%) |
|---|---|
| Tumor Location and Size | |
| Left | 8 (50) |
| Right | 7 (44) |
| Bilateral | 1 (6) |
| Size mean centimeters (range) | 10.3 (2.2–18) |
| Size median centimeters | 9.8 |
| General Tumor Features | |
| Unifocal | 15 (94) |
| Multifocal bilateral | 1 (6) |
| Infiltrative margin | 14 (88) |
| Circumscribed margin | 2 (12) |
| Large cystic or necrotic component | 8 (50) |
| Involvement of renal sinus fat | 13 (81) |
| Involvement of hilar collecting system | 8 (50) |
| Heterogenous enhancement | 16 (100) |
| Peritumoral vascularity | 9 (56) |
| Renal vein thrombus | 6 (38) |
| Retroperitoneal nodal metastases | 11 (69) |
| Distant metastases at presentation | 12 (75) |
| No metastases at presentation | 4 (25) |
| CT-Specific Tumor Features | |
| Calcifications | 0 |
| MRI-Specific Tumor Features | |
| T1 hemorrhage | 7 (58) |
| Intravoxel fat | 0 |
| T2 signal heterogeneity | 12 (100) |
| Diffusion restriction in solid component | 11 (100) |
| PET-Specific Tumor Features | |
| FDG avidity above liver background | 3 (100) |
| SUVmax mean (range) | 16.4 (9.6–21.9) |
