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Table 2 Texture features with significant difference obtained from virtual monochromatic CT images between lymph node metastases positive and negative groups of pancreatic ductal adenocarcinoma (155 cases)

From: Resectable pancreatic ductal adenocarcinoma: association between preoperative CT texture features and metastatic nodal involvement

Image subset

Texture feature

N+(n = 72)

N-(n = 83)

U/t

P value

AUC(95% CI)

P value

Cutoff value

+LR

1.25 mm-AP-60 keV

WavEnLH_s-2b

244 (208, 313)

294 (242, 352)

2209

0.005

0.630(0.549–0.706)

0.005

270

2.08

1.25 mm-PVP-60 keV

S(5,-5)SumAverga

62.5 ± 2.0

63.4 ± 2.1

2.657

0.009

0.619(0.538–0.696)

0.009

63.3

1.45

 

S(4,-4)SumAverga

62.5 ± 1.8

63.2 ± 1.9

2.303

0.023

0.600(0.518–0.677)

0.029

63.7

1.31

 

S(4,4)SumAverga

62.4 ± 1.8

63.0 ± 1.8

2.019

0.045

0.589(0.500–0.679)

0.052

NA

NA

 

S(4,0)SumAverga

62.7 ± 1.4

63.2 ± 1.6

1.995

0.048

0.594(0.512–0.672)

0.040

63.4

1.41

 

S(3,3)SumAverga

62.6 ± 1.6

63.2 ± 1.6

2.283

0.024

0.607(0.525–0.684)

0.019

62.6

1.67

 

S(2,2)SumAverga

62.9 ± 1.3

63.4 ± 1.3

2.216

0.028

0.615(0.534–0.692)

0.012

63.1

1.64

 

S(1,1)SumAverga

63.5 ± 0.8

63.7 ± 0.9

2.021

0.045

0.608(0.526–0.685)

0.019

63.6

1.60

5 mm-AP-65 keV

135dr_LngREmpha

1.24 ± 0.06

1.22 ± 0.06

−2.133

0.035

0.608(0.526–0.685)

0.019

1.23

1.57

 

S(4,-4)SumOfSqsa

100 ± 7

97 ± 9

−2.218

0.028

0.573(0.484–0.663)

0.110

NA

NA

 

135dr_Fractiona

0.929 ± 0.016

0.934 ± 0.015

2.088

0.038

0.612(0.530–0.689)

0.015

0.934

1.58

5 mm-PVP-65 keV

S(5,-5)SumAvergb

62.2(61.1, 63.4)

62.8(61.1, 64.6)

2429

0.045

0.594(0.512–0.672)

0.041

63.0

1.36

 

S(4,4)SumAverga

62.0 ± 1.8

62.6 ± 2.1

2.047

0.042

0.571(0.481–0.661)

0.121

NA

NA

  1. aData are mean ± standard deviation, independent samples t-test was used
  2. bData are median (quartile 1, quartile 3), Mann-Whitney test was used
  3. Abbreviation: AP late arterial phase, AUC area under receiver operator characteristic curve, CI confidence interval, keV kilo electron voltage, +LR positive likelihood ratio, n number of cases, N+ lymph node metastasis positive, N- lymph node metastasis negative, NA not applicable, PVP portal venous phase, SD standard deviation, t independent samples t-test, U Mann-Whitney test; 1.25 mm/5 mm, slice thickness of the CT images analysed