Table 2 Diagnostic performance on a patient basis for the detection of lymph node metastasis with pathology as reference. Data accuracy data from any comparative index test(s) are shown in parenthesis
Ref | Author | LNM (%) | Sens (%) | Spec (%) | PPV (%) | NPV (%) | Comparative index tests |
|---|---|---|---|---|---|---|---|
1 | Budaus et al. [16] | 40 | 33 | 100 | 100 | 69 | None |
2 | Herlemann et al. [17] | NR | 91 | 67 | 83 | 80 | None |
3 | Maurer et al. [18] | 32 | 66 (44) | 99 (85) | 96 (58) | 86 (77) | CT |
4 | Van Leeuwen et al. [19] | 37 | 64 | 95 | 88 | 82 | None |
5 | Uprimny et al. [20] | 37 | 61 | 94 | 85 | 81 | None |
6 | Gupta et al. [21] | 58 | 100 (57) | 80 (80) | 88 (80) | 100 (57) | MRI |
7 | Obek et al., [22] | 29 | 53 (25) | 86 (76) | 61.5 (NR) | 81 (NR) | MRI/CT |
8 | Zhang et al. [23] | 36 | 93 (96) | 96 (96) | 93 (88) | 96 (100) | mpMRI |
9 | Park et al. [24] | 9 | 100 | 87 | 43 | 100 | None |
10 | Van Leeuwen et al. [25] | 36 | 53 (14) | 88 (99) | 71 (81) | 76 (67) | DW-MRI |
11 | Gorin et al. [26] | 28 | 71 | 89 | 71 | 89 | None |
12 | Cantiello et al. [27] | 35 | 88 | 100 | 100 | 94 | None |
13 | Thalgott et al. [28]a | 34 | 60 | 100 | 100 | 83 | None |
14 | Berger et al. [29] | 4 | 50 (NR) | 92 (NR) | 20 (NR) | 98 (NR) | mpMRI |
15 | Gupta et al. [30] | 39 | 78 | 93 | 88 | 87 | None |
16 | Yaxley et al. [31] | 26 | 38 | 93 | 68 | 81 | None |
17 | Yilmaz et al. [32] | 20 | 100 (100) | 100 (38) | 100 (29) | 100 (29) | mpMRI |
18 | Petersen et al. [33]b | 65 | 23–39 (8;37) | 100 (100;83) | 100 (100;80) | 41–47 (37;42) | CT/MRI; DW-MRI |