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Fig. 3 | Cancer Imaging

Fig. 3

From: Relationship between clinicopathologic factors and FDG avidity in radioiodine-negative recurrent or metastatic differentiated thyroid carcinoma

Fig. 3

Forty-year-old female with papillary thyroid cancer, aggressive histopathologic type, underwent total thyroidectomy and then received 131I therapy with a total dose of 550 mCi. Diagnostic 131I whole-body scan after the 3rd treatment showed no abnormal uptake and the patient’s stimulated Tg was > 1000 ng/ml. PET (panel A and D), CT (panel B) and fused PET/CT (panel D) images showed markedly FDG-avid metastatic disease (SUVmax up to 35.55, cross-hair). Surgical resection of that lesion confirmed metastases of papillary thyroid carcinoma, immunohistochemistry and real-time PCR showed BRAF V600E mutation

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