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Table 3 Region-based sensitivities and specificities for WB-DWIBS/STIR and 18F-FDG-PET/CT

From: Assessment of naive indolent lymphoma using whole-body diffusion-weighted imaging and T2-weighted MRI: results of a prospective study in 30 patients

  Overall P Nodal P Extranodal P
Sensitivity§
WB-DWIBS/STIR (R1) 95.1 0.117 95.4 0.511 94.9 0.058
WB-DWIBS/STIR (R2) 93.4 93.0 96.8
18F-FDG-PET/CT (R1) 91.8 94.1 79.6
18F-FDG-PET/CT (R2) 89.3 91.1 86.3
Specificity§
WB-DWIBS/STIR (R1) 99.4 <  0.001 99.3 <  0.001 99.5 0.439
WB-DWIBS/STIR (R2) 99.0 98.8 99.3
18F-FDG-PET/CT (R1) 97.3 95.4 98.9
18F-FDG-PET/CT (R2) 95.6 92.1 98.6
  1. §Data does not reflect bone marrow involvement of lymphoma. Data are shown as percentages. Generalized estimating equations were used for sensitivity and specificity comparisons to allow multiple regions per patient to be taken into account. R1 observer 1, R2 observer 2, WB-DWIBS/STIR whole-body diffusion-weighted imaging with background body signal suppression and T2-weighted short-tau inversion recovery magnetic resonance imaging, 18F-FDG-PET/CT = 18F-fluorodeoxyglucose-positron emission tomography-computed tomography