Table 2 Comparison of PET/MRI with ceMRI and ceCT for patient-based T, N and M staging
From: Diagnostic value of 18F-FDG PET/MRI for staging in patients with endometrial cancer
| PET/MRI | ceMRI and ceCT | |
|---|---|---|
| Primary tumor | ||
| Sensitivity | 97.2% (35/36) | 97.2% (35/36) |
| T staging | ||
| Accuracy | 77.8% (28/36) | 75.0% (27/36) |
| ≥50% myometrial invasion | ||
| Sensitivity | 92.9% (13/14) | 92.9% (13/14) |
| Specificity | 86.4% (19/22) | 81.8% (18/22) |
| Accuracy | 88.9% (32/36) | 86.1% (31/36) |
| Invasion of cervical stroma | ||
| Sensitivity | 85.7% (6/7) | 71.4% (5/7) |
| Specificity | 100% (29/29) | 93.1% (27/29) |
| Accuracy | 97.2% (35/36) | 88.9% (32/36) |
| Invasion of uterine serosa | ||
| Sensitivity | 100% (1/1) | 100% (1/1) |
| Specificity | 100% (35/35) | 100% (35/35) |
| Accuracy | 100% (36/36) | 100% (36/36) |
| Invasion of adnexa | ||
| Sensitivity | 25.0% (1/4) | 25.0% (1/4) |
| Specificity | 100% (32/32) | 100% (32/32) |
| Accuracy | 91.7% (33/36) | 91.7% (33/36) |
| Invasion of vagina | ||
| Sensitivity | 50.0% (1/2) | 50.0% (1/2) |
| Specificity | 100% (34/34) | 100% (34/34) |
| Accuracy | 97.2% (35/36) | 97.2% (35/36) |
| Invasion of parametria | ||
| Sensitivity | 0% (0/1) | 0% (0/1) |
| Specificity | 100% (35/35) | 100% (35/35) |
| Accuracy | 97.2% (35/36) | 97.2% (35/36) |
| N staging | ||
| Accuracy | 91.3% (21/23) | 87.0% (20/23) |
| Metastatic pelvic lymph node | ||
| Sensitivity | 100% (2/2) | 50% (1/2) |
| Specificity | 90.5% (19/21) | 95.2% (20/21) |
| Accuracy | 91.3% (21/23) | 91.3% (21/23) |
| Metastatic para-aortic lymph node | ||
| Sensitivity | 100% (1/1) | 0% (0/1) |
| Specificity | 100% (13/13) | 100% (13/13) |
| Accuracy | 100% (14/14) | 92.9% (13/14) |
| M staging | ||
| Sensitivity | 33.3% (1/3) | 66.7% (2/3) |
| Specificity | 100% (8/8) | 87.5% (7/8) |
| Accuracy | 81.8% (9/11) | 81.8% (9/11) |