| |
Univariate analysis
|
Multivariate analysis
|
|---|
|
p value
|
HR
|
95%CI
|
p value
|
HR
|
95%CI
|
|---|
|
Age (years)
|
0.648
|
1.014
|
0.955–1.076
| | | |
|
Sex (female)
|
0.253
|
0.517
|
0.167–1.603
| | | |
|
Etiology (HCV)
|
0.963
|
0.974
|
0.313–3.025
| | | |
|
Child–Pugh class (A)
|
0.147
|
0.456
|
0.158–1.316
| | | |
|
Platelets (×104/μL)
|
0.139
|
1.033
|
0.990–1.078
| | | |
|
ALT (IU/L)
|
0.365
|
1.006
|
0.993–1.020
| | | |
|
Hyaluronic acid (ng/mL)
|
0.681
|
1.000
|
0.999–1.002
| | | |
|
Type IV collagen 7S (ng/mL)
|
0.070
|
1.150
|
0.989–1.338
| | | |
|
Tumor size (mm)
|
0.001
|
1.174
|
1.071–1.287
|
0.044
|
1.112
|
1.003–1.232
|
|
Number of tumors
|
0.037
|
2.035
|
1.044–3.965
|
0.535
|
1.315
|
0.554–3.122
|
|
AFP (ng/mL)
|
0.003
|
1.002
|
1.001–1.003
|
0.436
|
0.999
|
0.998–1.001
|
|
AFP-L3 (> 15%)
|
0.007
|
4.274
|
1.474–12.390
|
0.074
|
3.774
|
0.879–16.210
|
|
DCP (mAU/mL)
|
0.698
|
1.000
|
1.000–1.000
| | | |
|
PET positive
|
< 0.001
|
12.783
|
4.456–36.671
|
0.004
|
7.300
|
1.920–27.751
|
- HR hazard ratio, CI confidence interval, HCV hepatitis C virus, ALT alanine aminotransferase, HCC hepatocellular carcinoma, AFP alpha-fetoprotein, AFP-L3 Lens culinaris agglutinin-reactive alpha-fetoprotein, DCP Des-gamma-carboxyprothrombin, PET positron emission tomography
