| |
Univariate analysis
|
Multivariate analysis
|
|---|
|
p value
|
HR
|
95%CI
|
p value
|
HR
|
95%CI
|
|---|
|
Age (years)
|
0.619
|
0.989
|
0.949–1.032
| | | |
|
Sex (female)
|
0.592
|
0.818
|
0.391–1.708
| | | |
|
Etiology (HCV)
|
0.631
|
1.246
|
0.508–3.052
| | | |
|
Child–Pugh class (A)
|
0.027
|
0.426
|
0.200–0.906
|
0.087
|
0.449
|
0.180–1.123
|
|
Platelets (×104/μL)
|
0.588
|
1.014
|
0.965–1.064
| | | |
|
ALT (IU/L)
|
0.367
|
1.005
|
0.994–1.015
| | | |
|
Hyaluronic acid (ng/mL)
|
0.145
|
1.001
|
1.000–1.001
| | | |
|
Type IV collagen 7S (ng/mL)
|
0.018
|
1.141
|
1.023–1.274
|
0.454
|
1.057
|
0.914–1.222
|
|
Tumor size (mm)
|
0.000
|
1.132
|
1.062–1.207
|
0.017
|
1.089
|
1.015–1.169
|
|
Number of tumors
|
0.014
|
1.940
|
1.145–3.285
|
0.197
|
1.492
|
0.812–2.740
|
|
AFP (ng/mL)
|
0.012
|
1.001
|
1.000–1.002
|
0.534
|
1.000
|
0.998–1.001
|
|
AFP-L3 (> 15%)
|
0.030
|
2.559
|
1.096–5.972
|
0.329
|
1.703
|
0.585–4.961
|
|
DCP (mAU/mL)
|
0.775
|
1.000
|
1.000–1.000
| | | |
|
PET positive
|
< 0.001
|
12.941
|
4.646–36.047
|
< 0.001
|
10.297
|
3.128–33.898
|
- HR hazard ratio, CI confidence interval, HCV hepatitis C virus, ALT alanine aminotransferase, HCC hepatocellular carcinoma, AFP alpha-fetoprotein, AFP-L3, Lens culinaris agglutinin-reactive alpha-fetoprotein, DCP Des-gamma-carboxyprothrombin, PET positron emission tomography
