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Table 4 Univariate and multivariate analyses of factors related to metastatic recurrence

From: Prognostic value of 18F-fluorodeoxyglucose positron emission tomography in patients with small hepatocellular carcinoma treated by radiofrequency ablation

 

Univariate analysis

Multivariate analysis

p value

HR

95%CI

p value

HR

95%CI

Age (years)

0.619

0.989

0.949–1.032

   

Sex (female)

0.592

0.818

0.391–1.708

   

Etiology (HCV)

0.631

1.246

0.508–3.052

   

Child–Pugh class (A)

0.027

0.426

0.200–0.906

0.087

0.449

0.180–1.123

Platelets (×104/μL)

0.588

1.014

0.965–1.064

   

ALT (IU/L)

0.367

1.005

0.994–1.015

   

Hyaluronic acid (ng/mL)

0.145

1.001

1.000–1.001

   

Type IV collagen 7S (ng/mL)

0.018

1.141

1.023–1.274

0.454

1.057

0.914–1.222

Tumor size (mm)

0.000

1.132

1.062–1.207

0.017

1.089

1.015–1.169

Number of tumors

0.014

1.940

1.145–3.285

0.197

1.492

0.812–2.740

AFP (ng/mL)

0.012

1.001

1.000–1.002

0.534

1.000

0.998–1.001

AFP-L3 (> 15%)

0.030

2.559

1.096–5.972

0.329

1.703

0.585–4.961

DCP (mAU/mL)

0.775

1.000

1.000–1.000

   

PET positive

< 0.001

12.941

4.646–36.047

< 0.001

10.297

3.128–33.898

  1. HR hazard ratio, CI confidence interval, HCV hepatitis C virus, ALT alanine aminotransferase, HCC hepatocellular carcinoma, AFP alpha-fetoprotein, AFP-L3, Lens culinaris agglutinin-reactive alpha-fetoprotein, DCP Des-gamma-carboxyprothrombin, PET positron emission tomography