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Table 3 Univariate and multivariate analyses of factors related to recurrence

From: Prognostic value of 18F-fluorodeoxyglucose positron emission tomography in patients with small hepatocellular carcinoma treated by radiofrequency ablation

 

Univariate analysis

Multivariate analysis

p value

HR

95%CI

p value

HR

95%CI

Age (years)

0.520

1.008

0.983–1.034

   

Sex (female)

0.878

1.036

0.660–1.627

   

Etiology (HCV)

0.004

2.426

1.334–4.411

0.006

2.438

1.293–4.599

Child–Pugh class (A)

0.007

0.492

0.294–0.823

0.042

0.524

0.281–0.976

Platelets (×104/μL)

0.742

0.994

0.957–1.031

   

ALT (IU/L)

0.048

1.006

1.000–1.012

0.873

1.001

0.993–1.008

Hyaluronic acid (ng/mL)

< 0.001

1.001

1.001–1.002

0.575

1.000

0.999–1.001

Type IV collagen 7S (ng/mL)

0.000

1.146

1.073–1.224

0.130

1.080

0.978–1.192

Tumor size (mm)

0.037

1.040

1.002–1.079

0.573

1.012

0.971–1.054

Number of tumors

< 0.001

2.172

1.459–3.235

0.005

1.930

1.219–3.057

AFP (ng/mL)

0.120

1.001

1.000–1.001

   

AFP-L3 (> 15%)

0.084

1.725

0.929–3.205

   

DCP (mAU/mL)

0.282

1.000

1.000–1.000

   

PET positive

0.021

2.425

1.144–5.138

0.112

1.969

0.854–4.540

  1. HR hazard ratio, CI confidence interval, HCV hepatitis C virus, ALT alanine aminotransferase, HCC hepatocellular carcinoma, AFP alpha-fetoprotein, AFP-L3 Lens culinaris agglutinin-reactive alpha-fetoprotein, DCP, Des-gamma-carboxyprothrombin, PET positron emission tomography