| |
PET negative (n = 110)
|
PET positive (n = 11)
|
p value
|
|---|
|
Age (years)
|
69 (45–87)
|
76 (58–83)
|
0.401
|
|
Sex (male/female)
|
68/42
|
5/6
|
0.341
|
|
Etiology (HCV/non-HCV)
|
82/28
|
9/2
|
0.730
|
|
Fibrosis stage (F0–3/4)
|
39/71
|
5/6
|
0.526
|
|
Child–Pugh class (A/B)
|
87/23
|
10/1
|
0.691
|
|
Platelets (× 104/μL)
|
9.0 (2.4–75.9)
|
10.4 (2.9–21.2)
|
0.351
|
|
ALT (IU/L)
|
37 (10–171)
|
45 (16–133)
|
0.339
|
|
Hyaluronic acid (ng/mL)
|
216.3 (23.2–1851.9)
|
265.5 (85.0–884.9)
|
0.438
|
|
Type IV collagen 7S (ng/mL)
|
7.7 (3.0–18.0)
|
7.3 (4.1–12.9)
|
0.487
|
|
Tumor size (mm)
|
18 (8–30)
|
25 (15–30)
|
0.001
|
|
Number of tumors (1/2/3)
|
91/14/5
|
8/2/1
|
0.413
|
|
AFP (ng/mL)
|
16.1 (1.8–1594.5)
|
112.1 (3.1–1545.8)
|
0.011
|
|
AFP-L3 (%)
|
7.3 (0–72.5)
|
28.9 (0–80.0)
|
0.011
|
|
DCP (mAU/mL)
|
58 (5–9489)
|
177 (22–2615)
|
0.008
|
- HCV hepatitis C virus, ALT alanine aminotransferase, HCC hepatocellular carcinoma, AFP alpha-fetoprotein, AFP-L3 Lens culinaris agglutinin-reactive alpha-fetoprotein, DCP Des-gamma-carboxyprothrombin, PET positron emission tomography. Data are expressed as medians (range)