Skip to main content

Table 2 Blood Examination and Cognitive Assessment Results in Breast Cancer Group at Three Time Points

From: Network-level functional connectivity alterations in chemotherapy treated breast cancer patients: a longitudinal resting state functional MRI study

Median ± (IQRs)

P value

F value

P value

Characteristic

t0

t1

t2

t0 vs t1

t0 vs t2

t1 vs t2

E2 (pmol/L)

265.0 (112.3–391.8)

81.0 (52.0–125.0)

138.0 (84.5–195.0)

0.041

0.188

0.506

5.089

0.012c

FSH (IU/L)

6.9 (3.9–40.1)

70.1 (10.3–89.9)

64.6 (19.9–112.2)

0.031

0.385

0.965

2.958

0.075c

LH (IU/L)

7.3 (2.2–25.4)

34.5 (5.8–51.5)

7.6 (3.4–29.0)

0.662

0.926

0.156

3.344

0.106c

Hemoglobin (g/L)

124.0 (110.0–134.0)

121.0 (113.3–126.0)

133.0 (123.5–142.0)

0.989

0.325

0.003

3.876

0.075c

Fasting glucose (mmol/L)

5.2 (4.7–7.2)

5.4 (4.8–5.7)

5.4 (5.2–5.7)

0.677

0.523

0.832

0.215

0.808a

Total cholesterol (mmol/L)

4.9 (4.3–5.7)

5.0 (4.5–5.4)

4.9 (4.7–5.2)

0.745

0.732

0.990

0.076

0.927c

Triglycerides (mmol/L)

1.49 (0.9–3.0)

2.0 (1.44–3.70)

2.1 (1.90–2.70)

0.041

1.000

0.194

3.281

0.052a

SAS (score)

29.0 (27.0–31.8)

32 (32.0–35.0)

27.0 (23.3–34.8)

0.186

0.659

0.098

1.548

0.228a

SDS (score)

27.5 (24.5–32.0)

34.0 (33.0–34.0)

29.0 (24.0–41.5)

0.133

0.221

0.677

1.418

0.257c

Stroop-C (sec)

15.3 (13.5–18.4)

14.4 (12.9–15.5)

14.4 (12.9–15.5)

0.480

0.493

0.985

0.340

0.714c

Stroop-W (sec)

22.0 (18.5–26.1)

18.9 (17.1–20.1)

19.0 (14.4–19.6)

0.235

0.179

0.876

1.156

0.327c

Stroop-I (sec)

31.5 (24.9–33.0)

29.0 (25.0–34.7)

24.0 (20.0–42.0)

0.999

0.992

0.991

0.001

0.999c

NST (sec)

47.2 (39.8–62.0)

41.0 (39.5–51.5)

53.0 (40.0–71.0)

0.973

0.187

0.224

1.101

0.345c

DST (score)

49.5 (34.0–61.8)

54.0 (45.0–64.0)

59.0 (43.0–60.0)

0.798

0.855

0.672

0.093

0.912c

LTT (sec)

59.8 (46.1–83.2)

40.0 (28.2–48.5)

39.0 (30.8–56.0)

0.010

0.012

0.978

5.013

0.013c

MMSE (score)

28.0 (27.0–29.5)

29.0 (28.0–29.5)

27.5 (26.3–29.8)

0.431

0.301

0.879

0.619

0.545c

SDT (sec)

37.4 (33.3–42.3)

33.5 (30.9–38.7)

32.0 (27.8–36.9)

0.451

0.247

0.659

0.728

0.491c

WDT (score)

24.0 (22.0–27.0)

21.0 (17.5–27.5)

18.0 (11.5–22.5)

0.278

0.002

0.082

5.595

0.008c

  1. a: k-independent samples nonparametric tests; c: two-sample t test
  2. Abbreviations: t0 baseline assessment, t1 one week after chemotherapy, t2 six months after chemotherapy, SD standard deviation, E2 estradiol, FSH follicle stimulating hormone, LH luteinizing hormone, DST digit symbol test, MMSE Mini-mental state examination, LTT line tracing test, NCT number connection test, SDT Serial dotting test, SDS Self-Rating Depression Scale, SAS Self-Rating Anxiety Scale, Stroop-C Stroop colour test, Stroop-W Stroop word test, Stroop-I Stroop interference test, WDT Auditory verbal learning memory
Back to article page