Table 4 Performance evaluation of ADC parameters and nomogram model for differentiating occult IF and bone metastasis
Parameters | Cut off value | AUC (95% CI) | Sensitivity | Specificity | PPV | NPV |
|---|---|---|---|---|---|---|
ADC mean (×10−6 mm2/s) | 990 | 0.853 (0.756,0.950) | 85.4% (41/48) | 85.2% (23/27) | 91.1% (41/45) | 76.7% (23/30) |
ADC min (×10−6 mm2/s) | 828 | 0.743 (0.625, 0.861) | 70.8% (34/48) | 77.8% (21/27) | 85.0% (34/40) | 60.0% (21/35) |
ADC max (×10−6 mm2/s) | 1044 | 0.837 (0.732, 0.942) | 89.6% (43/48) | 77.8% (21/27) | 87.8% (43/49) | 80.8% (21/26) |
ADC std (×10−6 mm2/s) | 99.5 | 0.778 (0.670, 0.886) | 66.7% (32/48) | 88.9% (24/27) | 91.4% (32/35) | 60.0% (24/40) |
ADC ratio (Lesion/normal bone) | 3.75 | 0.853 (0.756, 0.950) | 85.4% (41/48) | 85.1% (23/27) | 91.1% (41/45) | 76.7% (23/30) |
ADC ratio (Lesion/lateral muscle) | 0.77 | 0.887 (0.793, 0.980) | 95.8% (46/48) | 81.5% (22/27) | 90.2% (46/51) | 91.7% (22/24) |
Nomogram model (score) | 0.97 | 0.921 (0.848, 0.995) | 91.7% (44/48) | 96.3% (26/27) | 97.8% (44/45) | 86.7%(26/30) |