Usefulness of 18F-FDOPA PET for the management of primary brain tumors: a systematic review of the literature

Cancer Imaging

Table 4 Optimal indices and cut-off that correlated with prognosis

Authors	Year	Patients (#)	Population	Optimal index and cut-off	P-value
Chiaravalloti et al.	2019	133	II = 68, III = 34, IV = 31	SUVr > 1.37	0.01
Isal et al.	2018	20	II = 13, III = 7	SUV_max T/N > 1.8	0.04
Rossi Espagnet et al.	2016	12	II = 12	SUV_max T/N > 1.7	0.05
Villani et al.	2015	50	II = 50	SUV_max > 1.75	0.005
Dowson et al.	2014	9	IV = 9	ΔSUV_max > 4.74	0.002
Herrmann et al.	2014	110	III = 33, IV = 77	SUVmean T/S > 1.06	< 0.001
Karunanithi et al.	2014	33	I = 2, II = 9, III = 6, IV = 16	SUV_max T/N > 1.51	0.005

SUVr Tumor uptake divided by contralateral occipital uptake, T/N Tumor uptake divided by normal brain uptake, T/S Tumor uptake divided by striatum uptake.

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