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Table 3 Performance of 18F-FDOPA in discriminating recurrence from post-therapeutic effects

From: Usefulness of 18F-FDOPA PET for the management of primary brain tumors: a systematic review of the literature

Authors

Year

Patients (#)

Sensitivity (%)

Specificity (%)

PPV (%)

NPV (%)

Accuracy (%)

Cut-off

Zaragori et al.

2020

51

97.1

94.1

NA

NA

96

T/S > 1

Youland et al.

2018

13

82

50

NA

NA

NA

T/N > 2.0

Karunanithi et al.a

2014

30

100

87.5

NA

NA

96

T/S > 0.6

Karunanithi et al.a

2013

35

100

88.9

NA

NA

97.1

NA (visual)

Herrmann et al.

2013

110

85.2

72.4

89.6

63.4

81.8

T/N > 1.81

Karunanithi et al.a

2013

28

100

85.7

NA

NA

96.4

T/N > 1.3

  1. NA Not available, NPV Negative predictive value, PPV Positive predictive value, T/N Tumor uptake divided by normal brain uptake, T/S Tumor uptake divided by striatum uptake
  2. a: the results of these studies are based on the same patient population