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Fig. 8 | Cancer Imaging

Fig. 8

From: The utility of pharmacological and radiological interventions to optimize diagnostic information from PET/CT

Fig. 8

Example of metformin effect. At baseline (a) metformin obscured uptake in a known rectal cancer. The baseline uptake in the primary tumour is demonstrated on the fused PET/MRI (b) but adjacent uptake in normal bowel compromised assessment of disease extent. The post-treatment scan (c) done with metformin withdrawal for 48 h demonstrated a complete metabolic response, which would otherwise have been impossible to discern

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