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Table 3 Diagnostic performances of whole-body bone SPECT/CT and FCH PET/CT in comparison with the best valuable comparator

From: Does whole-body bone SPECT/CT provide additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence?

 

Bone SPECT/CT (N = 115)

FCH PET/CT (N = 115)

True positive

N = 26

N = 28

True negative

N = 84

N = 85

False positive

N = 1

N = 0

False negative

N = 4

N = 2

Sensitivity

86.7% (69.3–96.2)

93.3 (77.9–99.2) %

Specificity

98.8% (93.6–100.0)

100.0 (95.8–100.0) %

Positive predictive value

96.3% (78.7–99.5)

100.0%

Negative predictive value

95.5% (89.4–98.1)

97.7 (91.8–99.4) %

AUC

0.824 (0.74–0.90)

0.829 (0.75–0.90)

  1. 95% CIs are given in parentheses
  2. AUC Area under the curve