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Table 3 Diagnostic performances of whole-body bone SPECT/CT and FCH PET/CT in comparison with the best valuable comparator

From: Does whole-body bone SPECT/CT provide additional diagnostic information over [18F]-FCH PET/CT for the detection of bone metastases in the setting of prostate cancer biochemical recurrence?

  Bone SPECT/CT (N = 115) FCH PET/CT (N = 115)
True positive N = 26 N = 28
True negative N = 84 N = 85
False positive N = 1 N = 0
False negative N = 4 N = 2
Sensitivity 86.7% (69.3–96.2) 93.3 (77.9–99.2) %
Specificity 98.8% (93.6–100.0) 100.0 (95.8–100.0) %
Positive predictive value 96.3% (78.7–99.5) 100.0%
Negative predictive value 95.5% (89.4–98.1) 97.7 (91.8–99.4) %
AUC 0.824 (0.74–0.90) 0.829 (0.75–0.90)
  1. 95% CIs are given in parentheses
  2. AUC Area under the curve