CT features associated with EGFR mutations and ALK positivity in patients with multiple primary lung adenocarcinomas

Table 2 Clinical comparison of multiple primary lung adenocarcinomas in different EGFR and ALK status (in pre-patients)

Variable	EGFR+ (n = 43)	EGFR- (n = 24)	Total	P	ALK+ (n = 13)	ALK-(n = 54)	Total	P
Age	56 ± 6	60 ± 8	58 ± 7	0.068	49 ± 7	58 ± 7	58 ± 7	0.002*
Gender				0.011*				0.099
Male	10(23)	13(54)	23(34)		7(54)	16(30)	23(34)
Female	33(77)	11(46)	44(66)		6(46)	35(4)	44(66)
History of smoking	8(19)	10(42)	18(27)	0.041*	2(14)	16(30)	18(27)	0.010*
Lymph node metastasis	10(23)	16(67)	26(30)	<0.001*	5(38)	8(15)	26(39)	0.110

* P values were based on comparisons between the two groups
EGFR epidermal growth factor receptor, ALK anaplastic large-cell lymphoma kinase
EGFR +, EGFR mutation; EGFR-, EGFR wild type mutation; ALK +, ALK positive; ALK-, ALK negative

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