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Table 1 CT features for lung adenocarcinoma

From: CT features associated with EGFR mutations and ALK positivity in patients with multiple primary lung adenocarcinomas

Variable Definition
Type Central, tumour located in the segmental or more proximal bronchi; peripheral, tumour located in the subsegmental bronchi or more distal airway
Location The distribution of each lesion in the lung was recorded, including left upper lobe, left lower lobe, right upper lobe, right middle lobe and right lower lobe
Relationship of location between multiple lesions in same patient Same lung segment, same lung lobe, ipsilateral lung and heterolateral lung
Tumor size Longest diameter of the tumor in MPR images
Ground glass opacity Ground glass dense nodules with internal vessels and bronchi visible
Mix ground glass opacity Composition of both ground glass opacity and solid
Pure ground glass opacity Composition of ground glass opacity only
Texture Predominantly solid, Tumour solid component / ground glass component > 0.5; Predominantly ground glass opacity, tumour solid diameter / ground glass diameter ≤ 0.5
Shape indicated as lobulated, others (round, or oval)
Lobulated The surface of the tumor showed as multiple arc-shaped projections
Margin Evaluated in the lung window, and indicated as smooth, or spiculated
Spiculate Evaluated in the lung window, and indicated as different degrees of spinous or burr-like protrusions at the tumour margin
Margin definition evaluated in the lung window, and indicated as well-defined, or poor-defined
Air bronchogram Tubelike or branched air structure within the tumour
Bubble-like lucency The 1 ~ 3 mm of air density area within the mass
Margins Evaluated in the lung window, and indicated as smooth, or spiculated
Heterogeneity Evaluated in the soft tissue window, and heterogeneity indicated as the difference of CT values in tumor was greater than 20HU
Pleural attachment Retraction of the pleura toward the tumour
Cavitation Presence or absence of cavitation
Intramodular calcifications Presence or absence of calcifications
Necrosis Low-density area in the tumour, without enhancement in enhance CT
Peripheral emphysema Presence or absence of peripheral emphysema
Peripheral fibrosis Pulmonary fibrosis around the tumor
Vascular convergence Convergence of vessels to the tumor, applied to the peripheral tumors
Enhancement mild” = 0 ~ 20 HU; “moderate” = 20 ~ 40 HU, “marked” > 40 HU
Lymphadenopathy presence or absence of lymphadenopathy thoracic lymph nodes (hilar or mediastinal) with short-axis diameter greater than 1 cm