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Table 1 CT features for lung adenocarcinoma

From: CT features associated with EGFR mutations and ALK positivity in patients with multiple primary lung adenocarcinomas

Variable

Definition

Type

Central, tumour located in the segmental or more proximal bronchi; peripheral, tumour located in the subsegmental bronchi or more distal airway

Location

The distribution of each lesion in the lung was recorded, including left upper lobe, left lower lobe, right upper lobe, right middle lobe and right lower lobe

Relationship of location between multiple lesions in same patient

Same lung segment, same lung lobe, ipsilateral lung and heterolateral lung

Tumor size

Longest diameter of the tumor in MPR images

Ground glass opacity

Ground glass dense nodules with internal vessels and bronchi visible

Mix ground glass opacity

Composition of both ground glass opacity and solid

Pure ground glass opacity

Composition of ground glass opacity only

Texture

Predominantly solid, Tumour solid component / ground glass component > 0.5; Predominantly ground glass opacity, tumour solid diameter / ground glass diameter ≤ 0.5

Shape

indicated as lobulated, others (round, or oval)

Lobulated

The surface of the tumor showed as multiple arc-shaped projections

Margin

Evaluated in the lung window, and indicated as smooth, or spiculated

Spiculate

Evaluated in the lung window, and indicated as different degrees of spinous or burr-like protrusions at the tumour margin

Margin definition

evaluated in the lung window, and indicated as well-defined, or poor-defined

Air bronchogram

Tubelike or branched air structure within the tumour

Bubble-like lucency

The 1 ~ 3 mm of air density area within the mass

Margins

Evaluated in the lung window, and indicated as smooth, or spiculated

Heterogeneity

Evaluated in the soft tissue window, and heterogeneity indicated as the difference of CT values in tumor was greater than 20HU

Pleural attachment

Retraction of the pleura toward the tumour

Cavitation

Presence or absence of cavitation

Intramodular calcifications

Presence or absence of calcifications

Necrosis

Low-density area in the tumour, without enhancement in enhance CT

Peripheral emphysema

Presence or absence of peripheral emphysema

Peripheral fibrosis

Pulmonary fibrosis around the tumor

Vascular convergence

Convergence of vessels to the tumor, applied to the peripheral tumors

Enhancement

mild” = 0 ~ 20 HU; “moderate” = 20 ~ 40 HU, “marked” > 40 HU

Lymphadenopathy

presence or absence of lymphadenopathy thoracic lymph nodes (hilar or mediastinal) with short-axis diameter greater than 1 cm