Fig. 2

Illustrative examples of qualitative imaging traits of ICC. a 46-year-old female with moderately differentiated ICC (AJCC stage 3). Axial high b-value (b = 800) diffusion-weighted image demonstrates a dominant tumor in left lateral hepatic lobe with multiple satellite nodules (defined as smaller tumor lesions within 2 cm of the dominant mass) (arrows) and metastatic lymphadenopathy (dashed arrow) adjacent to the liver. b 37-year-old female with moderately differentiated ICC (AJCC stage 1). CT acquired during the arterial phase demonstrates a large hypovascular caudate lobe and right hepatic lobe tumor (arrows) and associated right portal vein invasion (dashed arrow). c 48-year-old male with poorly differentiated ICC (AJCC stage 3). CT acquired during the arterial phase demonstrates a left hepatic lobe tumor (solid arrows) causing marked biliary obstruction (dashed arrows)