Table 5 Univariate and multivariate analyses of risk factors for MVI of ICCs
From: MRI features predict microvascular invasion in intrahepatic cholangiocarcinoma
Risk Factor | Univariate Analysis | Multivariate Analysis | ||
|---|---|---|---|---|
Odds Ratio (95% CI) | P value | Odds Ratio (95% CI) | P value | |
Age (years) | 1.047 (0.980–1.118) | 0.650 | … | … |
HBV | 1.100 (0.201–6.023) | 0.739 | … | … |
AFP ≥ 20 ng/ml | 0.166 (0.012–2.342) | 0.884 | … | … |
CEA ≥ 5 ng/ml | 0.832 (0.148–4.684) | 0.234 | … | … |
CA19–9 ≥ 37 U/ml | 1.991 (0.349–11.355) | 0.016 | 1.542 (0.552–4.310) | 0.409 |
Edmondson-Steiner grade | 0.068 (.004–1.114) | 0.668 | … | … |
Fibrosis stage | 25.104 (1.953–322.686) | 0.275 | … | … |
Liver cirrhosis | 0.207 (0.0140–3.065) | 0.715 | … | … |
Fatty liver | 0.961 (0.158–5.851) | 0.841 | … | … |
Tumor grade | 10.942 (1.664–71.956) | 0.007 | 3.076 (0.900–10.515) | 0.073 |
Tumor morphology | 1.493 (0.277–8.038) | 0.009 | 1.316 (0.383–4.529) | 0.663 |
Intrahepatic duct dilatation | 1.463 (0.335–6.387) | 0.003 | 1.497 (0.531–4.215) | 0.445 |
Hepatic capsular retraction | 1.100 (0.258–4.685) | 0.186 | … | … |
Target sign on DWI | 0.812 (0.191–3.446) | 0.739 | … | … |
Dynamic enhancement pattern | 4.020 (1.082–14.945) | 0.700 | … | … |
Arterial phase enhancement pattern | 2.080 (0.197–22.003) | 0.011 | 3.626 (0.505–26.036) | 0.200 |
Dot−/band-like enhancement inside the tumor | 0.308 (0.0566–1.676) | 0.089 | … | … |
Visible vessel penetration | 0.873 (0.087–8.743) | 0.099 | … | … |
Visible hepatic artery penetration | 6.835 (0.878–53.191) | 0.001 | 2.249 (0.609–8.313) | 0.224 |
Visible portal vein penetration | 0.472 (0.081–2.763) | 0.629 | … | … |
Visible hepatic vein penetration | 3.730 (0.564–24.651) | 0.111 | … | … |
Peripheral hepatic enhancement | 0.302 (0.054–1.676) | 0.615 | … | … |
Maximum diameter | 0.991 (0.951–1.032) | 0.001 | 1.013 (0.991–1.036) | 0.240 |
Arterial maximum thickness | 1.315 (1.019–1.696) | 0.354 | … | … |
Arterial enhanced edge integrity | 0.392 (0.075–2.057) | 0.110 | … | … |
Arterial edge enhancement ratio (%) | 0.874 (0.766–0.996) | 0.010 | 0.995 (0.966–1.025) | 0.760 |
Delayed phase enhancement ratio | 1.960 (0.819–4.687) | 0.812 | … | … |