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Table 4 Comparison of qualitative and quantitative Gd-DTPA enhancement MR imaging features according to MVI

From: MRI features predict microvascular invasion in intrahepatic cholangiocarcinoma

 

MVI-positive (n = 34)

MVI-negative (n = 74)

P value

Dynamic enhancement pattern

  

0.870

 Progressive

27 (79.41)

56 (75.68)

 

 Wash in-wash out

4 (11.76)

9 (12.16)

 

 Other

3 (8.82)

9 (12.16)

 

Arterial phase enhancement pattern

  

0.008

 Edged enhancement (ring high signal)

28 (82.35)

62 (83.78)

 

 Overall enhancement (high signal)

1 (2.94)

11 (14.86)

 

 Partial enhancement (mixed signal)

2 (5.88)

0 (0)

 

 No/mild enhancement (low signal)

3 (8.82)

1 (1.35)

 

Dot−/band-like enhancement inside the tumor

26 (76.47)

44 (59.46)

0.086

Absent

8 (23.53)

30 (40.54)

 

Visible vessel penetration

25 (73.53)

42 (56.76)

0.095

Absent

9 (26.47)

32 (43.24)

 

Visible hepatic artery penetration

12 (35.29)

6 (8.11)

0.000

Absent

22 (64.71)

68 (91.89)

 

Visible portal vein penetration

15 (44.12)

29 (39.19)

0.628

Absent

19 (55.88)

45 (60.81)

 

Visible hepatic vein penetration

17 (50)

25 (33.78)

0.108

Absent

17 (50)

49 (66.22)

 

Peripheral hepatic enhancement

18 (52.94)

43 (58.11)

0.615

Absent

16 (47.06)

31 (41.89)

 

Maximum diameter (cm)a

6.38 ± 3.06

4.45 ± 2.13

0.0003

 Maximum diameter ≤ 5 cmb

13 (38.24)

48 (64.86)

0.010

 Maximum diameter > 5 cm

21 (61.76)

26 (35.14)

 

Maximum enhancement edge-thickness in arterial phase (mm)b

3.95 (2.5, 14.3)

8.9 (3.8, 17.1)

0.0538

Arterial enhanced edge integrity

16 (47.06)

47 (63.51)

0.107

Arterial enhanced edge is incomplete

18 (52.94)

27 (36.49)

 

Arterial edge enhancement ratio (%)b

9.47 (4.26, 27.22)

21.48 (11.46, 42.19)

0.0002

Delayed phase enhancement ratio

  

1.000

 0 ≤ R < 1/4

5 (14.71)

10 (13.51)

 

 1/4 ≤ R < 2/4

1 (2.94)

2 (2.70)

 

 2/4 ≤ R < 3/4

5 (14.71)

10 (13.51)

 

 3/4 ≤ R ≤ 4/4

23 (67.65)

52 (70.27)

 
  1. The data are presented as the number (%) of patients
  2. aData are shown as the means±standard deviation. bData are shown as the median (25% percentile, 75% percentile)