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Table 8 Multivariate analysis for overall survival after first line immunotherapy

From: 18F-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Predictor

Level

HR

HR 95% CI

P-value

LDH

≤ULN

1

–

0.076

>ULN

2.13

[0.89, 5.08]

Stage

not M1c

1

–

0.163

M1c

1.88

[0.75, 4.75]

MTV

≤76

1

–

0.973

> 76

1.01

[0.51, 2.02]

ALC

≤1

1

–

0.164

> 1

0.61

[0.30, 1.21]

SLR

≤1.1

1

–

0.026

 

> 1.1

3.58

[1.34, 9.61]

 
  1. LDH Lactate dehydrogenase; ULN Upper limit of normal; MTV Metabolic Tumour Volume; ALC Absolute Lymphocyte Count; SLR Spleen to Liver Ratio
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Cancer Imaging

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