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Table 7 Multivariate analysis for progression free survival after ipilimumab

From: 18F-FDG PET/CT based spleen to liver ratio associates with clinical outcome to ipilimumab in patients with metastatic melanoma

Predictor

Level

HR

HR 95% CI

P-value

LDH

≤ULN

1

–

0.738

>ULN

1.12

[0.58, 2.14]

Stage

not M1c

1

–

0.431

M1c

1.32

[0.66, 2.67]

MTV

≤41

1

–

0.334

> 41

1.39

[0.71, 2.70]

ALC

≤1

1

–

0.083

> 1

0.55

[0.28, 1.06]

SLR

≤1.1

1

–

0.042

> 1.1

2.67

[1.13, 6.33]

  1. LDH Lactate dehydrogenase; ULN Upper limit of normal; MTV Metabolic Tumour Volume; ALC Absolute Lymphocyte Count; SLR Spleen to Liver Ratio