Fig. 17
From: What scans we will read: imaging instrumentation trends in clinical oncology
Super-resolution ultrasound. (a) Ultrafast Ultrasound Localization Microscopy (uULM) uses ultrasound devices with very high frame rates to achieve reliable tracks of microbubble movements. (b) In motion-model Ultrasound Localization Microscopy (mULM) tracks between voxels that are enhanced by microbubbles are generated, and their likelihood is calculated using a motion probability model. Three potential combinations are schematically displayed, with the green track symbolizing the highest probability. In uULM and mULM the diameter of the tracks is defined to be close to the size of microbubbles, and super-resolution images of the vasculature are generated. (c) B-Mode image of a breast cancer in a patient (encircled in white). (d) mULM based velocity map of a breast cancer in a patient. (e) The corresponding flow direction map, deriving from mULM analysis, provide important information about vessel maturity (image adapted from [166])