Table 1 Characteristics of patients in the training and validation cohorts
Characteristic | Training cohort (n = 96) | Validation cohort (n = 40) | P value |
|---|---|---|---|
Age | 0.925 | ||
Median | 60 (30–83) | 60 (42–86) | |
< 60 | 46 (47.0) | 18 (45.0) | |
≥ 60 | 50 (52.1) | 22 (55.0) | |
Gender | 0.906 | ||
Male | 90 (93.8) | 38 (95.0) | |
Female | 6 (6.25) | 2 (5.0) | |
Tumor location | 0.908 | ||
Supraglottic | 22 (22.9) | 8 (20.0) | |
Glottic | 71 (74.0) | 31 (77.5) | |
Subglottic | 3 (3.1) | 1 (2.5) | |
T classification | 0.733 | ||
T1 | 25 (26.0) | 13 (32.5) | |
T2 | 32 (33.3) | 13 (32.5) | |
T3 | 27 (28.1) | 8 (20.0) | |
T4 | 12 (12.5) | 6 (15.0) | |
N classification | 0.525 | ||
N0 | 78 (81.3) | 35 (87.5) | |
N1 | 11 (11.5) | 4 (10.0) | |
N2 | 7 (7.3) | 1 (2.5) | |
Cancer stage | 0.752 | ||
I | 25 (26.0) | 13 (32.5) | |
II | 28 (29.2) | 11 (27.5) | |
III | 29 (30.2) | 9 (22.5) | |
IV | 14 (14.6) | 7 (17.5) | |
Histological grade | 0.508 | ||
Well | 37 (38.5) | 17 (42.5) | |
Moderate | 36 (37.5) | 17 (42.5) | |
Poor | 23 (24.0) | 6 (15.0) | |
Laryngectomy | 0.196 | ||
Partial | 77 (80.2) | 28 (29.2) | |
Total | 19 (19.8) | 12 (12.5) | |
Adjuvant therapy | 0.792 | ||
No | 67 (69.8) | 27 (67.5) | |
Yes | 29 (30.2) | 13 (13.5) | |
Follow-up time (mo) | 0.959 | ||
Median | 42 (4–86) | 40 (5–82) | |
Rad-score | 0.646 | ||
Median | 4.34 (3.74–6.12) | 4.29 (3.95–5.98) |