Fig. 6
From: Nonprostatic diseases on PSMA PET imaging: a spectrum of benign and malignant findings
Bone PSMA uptake in correlation with morphology and other imaging modalities in two different patients. Patient 1, fibrous dysplasia (a-c). Axial CT (a) and axial 68Ga-PSMA-PET/CT (b) show a homogeneously sclerotic lesion with well-defined borders (arrow) and mild PSMA uptake (dashed arrow), suggestive of fibrous dysplasia. Previous MDP-bone scan lateral images (c) showed an intense osteogenic reaction (black arrow) in the right frontal bone, which is impossible to differentiate from a bone metastatis without a CT. Patient 2, Paget’s disease (d-j). Axial CT (d, e), axial 68Ga-PSMA-PET/CT (f, g) and axial T1w MR (i) images show mild uptake (arrows) in the cortical thickening and sclerosis of the right ischium (dashed arrows). Axial perfusion (h, j) MR images show an increased vascularization exactly in the same areas of the PSMA uptake (arrowheads). These findings are highly suggestive of Paget’s disease