Development and validation of a nomogram based on CT images and 3D texture analysis for preoperative prediction of the malignant potential in gastrointestinal stromal tumors

Table 3 Pre-scores of low-malignant and high-malignant potential GIST patients in training and validation sets

Characteristics	Training set		P-value	Validation set		P-value
Characteristics	Low-malignant group (n = 109)	High-malignant group (n = 199)	P-value	Low-malignant group (n = 47)	High-malignant group (n = 85)	P-value
Size (mean ± SD, cm)	3.01 ± 1.01	8.22 ± 3.99	< 0.001	3.17 ± 1.01	8.46 ± 4.44	< 0.001
Cystoid variation (%)			< 0.001			< 0.001
+	31 (28.44%)	154 (77.39%)		15 (31.91%)	67 (78.82%)
–	78 (71.56%)	45 (22.61%)		32 (68.09%)	18 (21.18%)
meanValue	66.07 (54.55, 88.27) ^*	51.19 (41.45, 65.41) ^*	< 0.001	64.52 (53.34, 86.89) ^*	51.39 (39.91, 64.50) ^*	< 0.001
Pre-score	−0.38 (−0.67, −0.05) ^*	1.44 (0.65, 2.73) ^*	< 0.001	−0.38 (−0.62, −0.01) ^*	1.44 (0.58, 3.06) ^*	< 0.001

Note: Size: the maximal diameter on the largest cross section of tumor; ^*Values refer to median (interquartile range (IQR)); P-values were the results of univariable association analyses of each characteristic and of the two groups; SD standard deviation; Pre-score prediction score

ISSN: 1470-7330