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Table 1 GISTs risk classification of NIH (2008)

From: Development and validation of a nomogram based on CT images and 3D texture analysis for preoperative prediction of the malignant potential in gastrointestinal stromal tumors

Risk category

Tumor size (cm)

Mitotic index (per 50 HPFs)

Primary tumor site

Very low risk

< 2.0

≤5

Any

Low risk

2.1–5.0

≤5

Any

Intermediate risk

2.1–5.0

> 5

Gastric

< 5.0

6–10

Any

5.1–10.0

≤5

Gastric

High risk

Any

Any

Tumor rupture

> 10

Any

Any

Any

> 10

Any

> 5

> 5

Any

2.1–5.0

> 5

Nongastric

5.1–10.0

≤5

Nongastric

  1. Note: NIH National Institutes of Health