Table 3 Subgroup analysis for the diagnostic performance of DWI on overall level
Characteristic | No.of Studies | Sensitivity (95% CI) | Specificity (95% CI) | I2 index of Sensitivity/Specificity | AUC (95% CI) | P Value |
|---|---|---|---|---|---|---|
All studies | 12 | 0.85(0.74–0.92) | 0.83(0.75–0.88) | 85.0/65.3 | 0.90(0.87–0.92) |  |
Study design | ||||||
 Retrospective | 5 | 0.80(0.73–0.86) | 0.81(0.71–0.88) | 0.00/69.6 | 0.86(0.83–0.89) | 0.68 |
 Prospective | 7 | 0.91(0.69–0.98) | 0.82(0.74–0.88) | 92.1/67.5 | 0.88(0.85–0.90) |  |
b value | ||||||
 < 800 | 5 | 0.88(0.69–0.96) | 0.92(0.83–0.96) | 67.5/0.00 | 0.93(0.91–0.95) | 0.40 |
 ≥ 800 | 6 | 0.85(0.75–0.92) | 0.76(0.66–0.83) | 58.8/49.2 | 0.87(0.83–0.89) |  |
Threshold method | ||||||
 visual | 6 | 0.82(0.71–0.89) | 0.82(0.67–0.91) | 38.663.1 | 0.88(0.85–0.90) | 0.47 |
 ADC | 6 | 0.87(0.65–0.96) | 0.85(0.76–0.91) | 92.9/72.7 | 0.90(0.87–0.92) |  |