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Table 3 Presurgical imaging modalities and association with level of axillary nodal burden on pathology

From: Breast MRI and tumour biology predict axillary lymph node response to neoadjuvant chemotherapy for breast cancer

 

No residual macrometastatic nodes n (%)

1–2 residual metastatic nodes n (%)

More than 2 residual metastatic nodes n (%)

p-value

Total

33 (38%)

28 (32%)

26 (30%)

 

MRI breast tumour phenotype:

 Mass

21 (41%)

20 (39%)

10 (20%)

 

 Non-mass enhancement

4 (33%)

4 (33%)

4 (33%)

0.091

 Both

8 (33%)

4 (17%)

12 (50%)

 

MRI breast interim chemo:

 Complete response

10 (90%)

0

1 (10%)

 

 Partial response

18 (40%)

18 (40%)

9 (20%)

< 0.0001

 Stable disease

3 (11%)

9 (33%)

15 (56%)

 

 Progressive disease

0 (0%)

0 (0%)

0 (0%)

 

MRI breast post chemo:

 Complete response

25 (64%)

9 (23%)

5 (13%)

< 0.0001

 Partial response

6 (15%)

16 (40%)

18 (45%)

 

 Stable disease

2 (40%)

2 (40%)

1 (20%)

 

 Progressive disease

0 (0%)

1 (100%)

0 (0%)

 

MRI axilla post chemo:

 Normal

21 (46%)

13 (28%)

12 (26%)

0.087

 Borderline

7 (39%)

7 (39%)

4 (22%)

 

 Abnormal (partial response)

5 (31%)

3 (19%)

8 (50%)

 

 Abnormal

0 (0%)

5 (71%)

2 (29%)