Table 3 Prediction results of radiomics models from diverse VOIs on the independent validation cohorts
Dataset | Image | Radiomics model | Feature number | AUC | 95% CI | p-Value | SEN | SPE | ACCU |
|---|---|---|---|---|---|---|---|---|---|
NPC group | CET1-w | Baseline | 15 | 0.778 | 0.720–0.830 | – | 77.4% | 75.0% | 72.7% |
Erosion | 9 | 0.806 | 0.750–0.855 | 0.403 | 77.4% | 85.7% | 76.9% | ||
Smoothing | 11 | 0.803 | 0.746–0.852 | 0.412 | 80.6% | 75.0% | 74.1% | ||
Dilation | 10 | 0.810 | 0.754–0.858 | 0.268 | 80.6% | 71.4% | 72.0% | ||
Dilation5 | 20 | 0.751 | 0.691–0.805 | 0.437 | 87.1% | 53.6% | 68.1% | ||
Dilation7 | 14 | 0.738 | 0.678–0.793 | 0.220 | 77.4% | 67.9% | 68.3% | ||
T2-w | Baseline | 11 | 0.748 | 0.688–0.802 | – | 74.2% | 71.4% | 70.8% | |
Erosion | 19 | 0.710 | 0.647–0.767 | 0.359 | 71.0% | 71.4% | 68.3% | ||
Smoothing | 15 | 0.702 | 0.639–0.759 | 0.279 | 74.2% | 60.7% | 66.1% | ||
Dilation | 20 | 0.718 | 0.656–0.774 | 0.447 | 77.4% | 60.7% | 65.8% | ||
Dilation5 | 14 | 0.596 | 0.530–0.659 | 0.003* | 54.8% | 53.6% | 53.4% | ||
Dilation7 | 18 | 0.588 | 0.522–0.651 | 0.002* | 61.3% | 64.3% | 57.3% | ||
SLN group | DWI | Baseline | 15 | 0.734 | 0.666–0.794 | – | 77.8% | 67.7% | 69.0% |
Erosion | 10 | 0.536 | 0.500–0.607 | <  0.001* | 55.6% | 58.1% | 54.7% | ||
Smoothing | 20 | 0.711 | 0.642–0.773 | 0.617 | 72.2% | 67.7% | 63.9% | ||
Dilation | 20 | 0.737 | 0.670–0.798 | 0.934 | 77.8% | 64.5% | 66.7% | ||
Dilation5 | 20 | 0.744 | 0.677–0.803 | 0.934 | 66.7% | 80.6% | 68.2% | ||
Dilation7 | 8 | 0.789 | 0.725–0.843 | 0.269 | 83.3% | 74.2% | 72.9% | ||
T2-FS | Baseline | 19 | 0.725 | 0.657–0.786 | – | 61.1% | 74.2% | 66.5% | |
Erosion | 20 | 0.696 | 0.627–0.760 | 0.319 | 55.6% | 77.4% | 61.0% | ||
Smoothing | 4 | 0.845 | 0.787–0.893 | 0.001* | 72.2% | 74.2% | 70.6% | ||
Dilation | 20 | 0.800 | 0.737–0.854 | 0.042* | 66.7% | 74.2% | 70.8% | ||
Dilation5 | 18 | 0.868 | 0.813–0.912 | < 0.001* | 77.8% | 87.1% | 76.5% | ||
Dilation7 | 13 | 0.802 | 0.739–0.855 | 0.028* | 83.3% | 67.7% | 72.9% |