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Table 5 Features based predictors that discriminate indolent grade cancer (Gleason = 6 Vs Benign) from benign a) univariate semantic predictors b) multivariable semantic predictors (up to 3 semantics) c) PIRADS based predictor

From: Radiological semantics discriminate clinically significant grade prostate cancer

  Features Error Sensitivity/Specificity PPV/NPV E [AUC],σ, [CI]
A) Single Predictive Semantic: Gleason 6 Vs Benign || Samples: 110 (33 Vs 77)
 1 F11:extraprostatic-extension-R 0.279 0.058/1 0.34/0.71 0.586 (0.12) [0.307,0.822]
 2 F7:early-enhancement-R 0.301 0/1 0/0.688 0.609 (0.1) [0.391,0.842]
 3 F4:ADC-intensity 0.319 0.014/0.98 0.006/0.702 0.614 (0.119) [0.348,0.928]
 4 F6:enhacement-degree 0.31 0.026/0.982 0.049/0.706 0.562 (0.126) [0.328,0.815]
 5 F3:T2-intensity 0.308 0/1 0/0.701 0.546 (0.103) [0.35,0.775]
B) Multivariable Semantic Predictor: GS 6 Vs Benign || Samples 110 (33 Vs 77)
 1 F5:homogeneity-R;F7:early-enhancement-R:F11:extraprostatic-extension-R 0.287 0.204/0.954 0.571/0.735 0.627 (0.137), [0.347,0.931]
 2 F4:ADC-intensity;F7:early-enhancement-R:F11:extraprostatic-extension-R 0.295 0.156/0.954 0.514/0.725 0.632 (0.114), [0.385,0.822]
 3 F3:T2-intensity;F7:early-enhancement-R:F11:extraprostatic-extension-R 0.305 0.157/0.947 0.404/0.743 0.624 (0.136), [0.406,0.909]
 4 F5:homogeneity-R;F7:early-enhancement-R:F11:extraprostatic-extension-R 0.287 0.204/0.954 0.571/0.735 0.627 (0.137), [0.347,0.931]
C) PIRADS as a Predictor (GS 6 Vs Benign) || Samples: 110 (33 Vs 77)
 1 PIRADS(≥ 3) 0.544 0.878/0.271 0.344/0.839 0.575 (0.083) [0.358,0.744]
 2 PIRADS(≥ 4) 0.44 0.769/0.468 0.384/0.823 0.618 (0.094) [0.393,0.775]
 3 PIRADS(≥ 5) 0.286 0.102/0.978 0.449/0.716 0.54 (0.062) [0.46,0.689]