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Table 3 Reproducibility of Semantics features and PIRADS scored between two radiologists on randomly selected prostate patients with 40 targeted biopsies (32 unique patients). A) Actual scores b) sorted scores

From: Radiological semantics discriminate clinically significant grade prostate cancer

Semantic Features

#

Features

Kappa (CI)

1

F1:shape

0.56 [0.33, 0.80]

2

F2:border

0.74 [0.55, 0.93]

3

F3:T2-intensity

0.58 [0.33, 0.84]

4

F4:ADC-intensity

0.6 [0.369, 0.83]

5

F5:homogeneity

0.55 [0.30, 0.81]

6

F6:enhacement-degree

0.67 [0.48, 0.86]

7

F7:early-enhancement

0.86 [0.66, 1.05]

8

F8:enhanced-homogenicity

0.70 [0.47, 0.92]

9

F9:capsule

0.54 [0.04, 1.04]

10

F10:cyst

1 [1,1]

11

F11:extraprostatic-extension

0.69 [0.49, 0.9]

12

F12:seminal-vesicles

NA

13

F13:distal-sphincter

NA

14

F14:bladder-neck

NA

15

F15:lymph-adenopathy

NA

16

F16:BPH

0.72 [0.49, 0.95]

PIRADS

0.69 [0.47, 0.90]

 

Kappa range

# Features

Details

1

≥0.7

4

F10:Cyst, F7:Early-enhancement, F2:Border,F16:BPH

2

≥0.6, < 0.7

4

F8:Enhanced-homogenic, F11:extraprostatic-extension, F6:enhacement-degree, F4:ADC-intensity

3

≥0.5, < 0.6

4

F3:T2-intensity, F1:Shape,F5:homogeneity, F9:capsule

4

NA (can’t evaluate)

4

F12:seminal-vesicles, F13:distal-sphincter;F14:bladder-neck, F15:lymph-adenopathy.

  1. NA: Not enough examples to compute kappa score